Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 100694..101238 Replicon chromosome
Accession NZ_CP017020
Organism Xanthomonas citri pv. malvacearum strain MSCT

Toxin (Protein)


Gene name relE Uniprot ID A0A7X9UUA0
Locus tag BGK55_RS00420 Protein ID WP_033479617.1
Coordinates 100939..101238 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A828YMS8
Locus tag BGK55_RS00415 Protein ID WP_005912560.1
Coordinates 100694..100951 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BGK55_RS00400 95826..97295 - 1470 WP_005912554.1 ribonuclease H-like domain-containing protein -
BGK55_RS00405 97292..99787 - 2496 WP_005912556.1 DEAD/DEAH box helicase -
BGK55_RS00410 99965..100627 + 663 WP_005912558.1 hemolysin III family protein -
BGK55_RS00415 100694..100951 + 258 WP_005912560.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BGK55_RS00420 100939..101238 + 300 WP_033479617.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BGK55_RS00430 101418..102317 - 900 WP_005912564.1 SDR family NAD(P)-dependent oxidoreductase -
BGK55_RS00435 102376..103113 - 738 WP_005912566.1 SDR family oxidoreductase -
BGK55_RS00440 103239..104150 + 912 WP_005912568.1 LysR family transcriptional regulator -
BGK55_RS00445 104349..105059 + 711 WP_005912570.1 hypothetical protein -
BGK55_RS00450 105250..105756 - 507 WP_005912572.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11246.00 Da        Isoelectric Point: 9.7235

>T65812 WP_033479617.1 NZ_CP017020:100939-101238 [Xanthomonas citri pv. malvacearum]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VVVHVMRSERALRGNRLSR

Download         Length: 300 bp

>T65812 NZ_CP017020:100939-101238 [Xanthomonas citri pv. malvacearum]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATCGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGGTGGTGCACGTCATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9646.15 Da        Isoelectric Point: 8.6223

>AT65812 WP_005912560.1 NZ_CP017020:100694-100951 [Xanthomonas citri pv. malvacearum]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVAEGRTLSHEQAQQRM
ARWLK

Download         Length: 258 bp

>AT65812 NZ_CP017020:100694-100951 [Xanthomonas citri pv. malvacearum]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGTGGAGAAATGGCAGTTGCGGAAGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7X9UUA0

Antitoxin

Source ID Structure
AlphaFold DB A0A828YMS8

References