Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6231429..6231948 Replicon chromosome
Accession NZ_CP017009
Organism Pseudomonas syringae pv. actinidiae strain NZ-47

Toxin (Protein)


Gene name relE Uniprot ID S6W9N2
Locus tag PsaNZ47_RS30135 Protein ID WP_017684310.1
Coordinates 6231429..6231719 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag PsaNZ47_RS30140 Protein ID WP_002551444.1
Coordinates 6231709..6231948 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PsaNZ47_RS30100 6227759..6228301 + 543 WP_017684306.1 hypothetical protein -
PsaNZ47_RS30105 6228365..6228648 - 284 Protein_5489 type II toxin-antitoxin system RelE/ParE family toxin -
PsaNZ47_RS30110 6228638..6228880 - 243 WP_017684307.1 hypothetical protein -
PsaNZ47_RS30115 6229061..6229675 - 615 WP_017684308.1 histidine phosphatase family protein -
PsaNZ47_RS30120 6229768..6230109 - 342 WP_003380754.1 hypothetical protein -
PsaNZ47_RS30125 6230466..6231203 + 738 WP_017684309.1 hypothetical protein -
PsaNZ47_RS30135 6231429..6231719 - 291 WP_017684310.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PsaNZ47_RS30140 6231709..6231948 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PsaNZ47_RS30145 6232124..6232585 - 462 WP_017684311.1 GNAT family N-acetyltransferase -
PsaNZ47_RS30150 6232672..6233241 - 570 WP_017684312.1 GNAT family N-acetyltransferase -
PsaNZ47_RS30155 6233402..6233896 + 495 WP_005621707.1 hypothetical protein -
PsaNZ47_RS30160 6234169..6234516 + 348 WP_017684314.1 helix-turn-helix domain-containing protein -
PsaNZ47_RS30165 6234602..6235876 - 1275 WP_003380766.1 OprD family porin -
PsaNZ47_RS30170 6236106..6236312 - 207 WP_044392902.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11145.98 Da        Isoelectric Point: 10.0984

>T65803 WP_017684310.1 NZ_CP017009:c6231719-6231429 [Pseudomonas syringae pv. actinidiae]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLGG

Download         Length: 291 bp

>T65803 NZ_CP017009:c6231719-6231429 [Pseudomonas syringae pv. actinidiae]
ATGACTTATAGCCTCGAATTTGATGCGCGAGCTCTGAAGGAATGGCACAAATTAGGCGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCAAATCGCCTGCATGCGTTGCCCGACTGCTACAAAATCA
AGCTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGGGTGGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT65803 WP_002551444.1 NZ_CP017009:c6231948-6231709 [Pseudomonas syringae pv. actinidiae]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT65803 NZ_CP017009:c6231948-6231709 [Pseudomonas syringae pv. actinidiae]
ATGGCGTCTATTAATGTTCGTATCGACGACGATCTCAAGGCTCGTGCTTATCTCGAGCTTGAAAAGCTTGGCGTCACCCC
TTCGGAACTGCTGCGCCAAACCCTGCAGTACGTGGCAGAGCGCGGCCAGTTGCCGTTCAAGACCGTACTGATGACCGAGG
AAGACGAAGCCTTGCTTGCAACAGTGCGCGAGCGCCTTGCGGCTCCGCAACGGGTCAAGGTTTCACTGGATGACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8M1I3

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References