Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 6350551..6351070 Replicon chromosome
Accession NZ_CP017007
Organism Pseudomonas syringae pv. actinidiae strain ICMP 20586

Toxin (Protein)


Gene name relE Uniprot ID S6W9N2
Locus tag PsaNZ45_RS30760 Protein ID WP_017684310.1
Coordinates 6350551..6350841 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag PsaNZ45_RS30765 Protein ID WP_002551444.1
Coordinates 6350831..6351070 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PsaNZ45_RS30725 6346881..6347423 + 543 WP_017684306.1 hypothetical protein -
PsaNZ45_RS30730 6347487..6347770 - 284 Protein_5609 type II toxin-antitoxin system RelE/ParE family toxin -
PsaNZ45_RS30735 6347760..6348002 - 243 WP_017684307.1 hypothetical protein -
PsaNZ45_RS30740 6348183..6348797 - 615 WP_017684308.1 histidine phosphatase family protein -
PsaNZ45_RS30745 6348890..6349231 - 342 WP_003380754.1 hypothetical protein -
PsaNZ45_RS30750 6349588..6350325 + 738 WP_017684309.1 hypothetical protein -
PsaNZ45_RS30760 6350551..6350841 - 291 WP_017684310.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PsaNZ45_RS30765 6350831..6351070 - 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PsaNZ45_RS30770 6351246..6351707 - 462 WP_017684311.1 GNAT family N-acetyltransferase -
PsaNZ45_RS30775 6351794..6352363 - 570 WP_017684312.1 GNAT family N-acetyltransferase -
PsaNZ45_RS30780 6352524..6353018 + 495 WP_005621707.1 hypothetical protein -
PsaNZ45_RS30785 6353291..6353638 + 348 WP_017684314.1 helix-turn-helix domain-containing protein -
PsaNZ45_RS30790 6353724..6354998 - 1275 WP_003380766.1 OprD family porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11145.98 Da        Isoelectric Point: 10.0984

>T65795 WP_017684310.1 NZ_CP017007:c6350841-6350551 [Pseudomonas syringae pv. actinidiae]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLGG

Download         Length: 291 bp

>T65795 NZ_CP017007:c6350841-6350551 [Pseudomonas syringae pv. actinidiae]
ATGACTTATAGCCTCGAATTTGATGCGCGAGCTCTGAAGGAATGGCACAAATTAGGCGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCAAATCGCCTGCATGCGTTGCCCGACTGCTACAAAATCA
AGCTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGGGTGGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT65795 WP_002551444.1 NZ_CP017007:c6351070-6350831 [Pseudomonas syringae pv. actinidiae]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT65795 NZ_CP017007:c6351070-6350831 [Pseudomonas syringae pv. actinidiae]
ATGGCGTCTATTAATGTTCGTATCGACGACGATCTCAAGGCTCGTGCTTATCTCGAGCTTGAAAAGCTTGGCGTCACCCC
TTCGGAACTGCTGCGCCAAACCCTGCAGTACGTGGCAGAGCGCGGCCAGTTGCCGTTCAAGACCGTACTGATGACCGAGG
AAGACGAAGCCTTGCTTGCAACAGTGCGCGAGCGCCTTGCGGCTCCGCAACGGGTCAAGGTTTCACTGGATGACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8M1I3

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References