Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-YafN |
Location | 4745857..4746382 | Replicon | chromosome |
Accession | NZ_CP017007 | ||
Organism | Pseudomonas syringae pv. actinidiae strain ICMP 20586 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A0K8M609 |
Locus tag | PsaNZ45_RS22990 | Protein ID | WP_017684329.1 |
Coordinates | 4746092..4746382 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A0K8M645 |
Locus tag | PsaNZ45_RS22985 | Protein ID | WP_017684328.1 |
Coordinates | 4745857..4746102 (+) | Length | 82 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PsaNZ45_RS22980 | 4741773..4745684 | - | 3912 | WP_020365655.1 | ATP-dependent RNA helicase HrpA | - |
PsaNZ45_RS22985 | 4745857..4746102 | + | 246 | WP_017684328.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
PsaNZ45_RS22990 | 4746092..4746382 | + | 291 | WP_017684329.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
PsaNZ45_RS22995 | 4746509..4748200 | - | 1692 | WP_003382607.1 | long-chain-fatty-acid--CoA ligase FadD1 | - |
PsaNZ45_RS23000 | 4748556..4750244 | - | 1689 | WP_017684330.1 | long-chain-fatty-acid--CoA ligase FadD2 | - |
PsaNZ45_RS23010 | 4750640..4751110 | + | 471 | WP_003382605.1 | MaoC family dehydratase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11019.86 Da Isoelectric Point: 10.4180
>T65792 WP_017684329.1 NZ_CP017007:4746092-4746382 [Pseudomonas syringae pv. actinidiae]
MTFKLEFLPSALKEWKKLGHTVSAQLKKKLLERLELPRNAGDALHGMPDHYKIKLRSAGYRLVYRVEDDRVVVTVVAVGK
RERGDIYDSAKDRLSP
MTFKLEFLPSALKEWKKLGHTVSAQLKKKLLERLELPRNAGDALHGMPDHYKIKLRSAGYRLVYRVEDDRVVVTVVAVGK
RERGDIYDSAKDRLSP
Download Length: 291 bp
>T65792 NZ_CP017007:4746092-4746382 [Pseudomonas syringae pv. actinidiae]
TTGACCTTTAAGCTCGAGTTTCTGCCTTCAGCCCTGAAAGAGTGGAAAAAACTGGGGCATACCGTTAGTGCTCAACTCAA
GAAAAAGCTTTTGGAGCGGCTCGAATTACCTCGAAATGCGGGCGATGCGCTGCATGGCATGCCCGATCACTACAAAATCA
AGTTGCGCAGTGCTGGTTACAGACTGGTTTACCGGGTGGAAGATGATCGGGTAGTAGTGACCGTCGTCGCTGTAGGCAAG
CGCGAACGAGGCGATATCTACGATTCAGCCAAGGACAGGCTGTCTCCCTGA
TTGACCTTTAAGCTCGAGTTTCTGCCTTCAGCCCTGAAAGAGTGGAAAAAACTGGGGCATACCGTTAGTGCTCAACTCAA
GAAAAAGCTTTTGGAGCGGCTCGAATTACCTCGAAATGCGGGCGATGCGCTGCATGGCATGCCCGATCACTACAAAATCA
AGTTGCGCAGTGCTGGTTACAGACTGGTTTACCGGGTGGAAGATGATCGGGTAGTAGTGACCGTCGTCGCTGTAGGCAAG
CGCGAACGAGGCGATATCTACGATTCAGCCAAGGACAGGCTGTCTCCCTGA
Antitoxin
Download Length: 82 a.a. Molecular weight: 8860.38 Da Isoelectric Point: 4.9721
>AT65792 WP_017684328.1 NZ_CP017007:4745857-4746102 [Pseudomonas syringae pv. actinidiae]
MQNIFADIAVSVSELKKNPSAVLSGAQGLPVAVLNHNKVMGYMVPAEVFEAMMKRLDDLDLADLIKARQHEKPVSVDILD
L
MQNIFADIAVSVSELKKNPSAVLSGAQGLPVAVLNHNKVMGYMVPAEVFEAMMKRLDDLDLADLIKARQHEKPVSVDILD
L
Download Length: 246 bp
>AT65792 NZ_CP017007:4745857-4746102 [Pseudomonas syringae pv. actinidiae]
ATGCAAAATATCTTTGCGGACATCGCGGTCAGCGTCTCTGAACTGAAGAAAAACCCGTCAGCCGTCCTGAGCGGCGCACA
AGGCTTGCCCGTCGCAGTACTCAATCACAATAAAGTCATGGGCTACATGGTGCCTGCCGAGGTGTTTGAAGCAATGATGA
AGCGCCTTGATGACCTCGATCTGGCCGACCTGATCAAAGCCAGGCAACATGAAAAGCCGGTATCGGTAGATATACTTGAC
CTTTAA
ATGCAAAATATCTTTGCGGACATCGCGGTCAGCGTCTCTGAACTGAAGAAAAACCCGTCAGCCGTCCTGAGCGGCGCACA
AGGCTTGCCCGTCGCAGTACTCAATCACAATAAAGTCATGGGCTACATGGTGCCTGCCGAGGTGTTTGAAGCAATGATGA
AGCGCCTTGATGACCTCGATCTGGCCGACCTGATCAAAGCCAGGCAACATGAAAAGCCGGTATCGGTAGATATACTTGAC
CTTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8M609 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8M645 |