Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 4745857..4746382 Replicon chromosome
Accession NZ_CP017007
Organism Pseudomonas syringae pv. actinidiae strain ICMP 20586

Toxin (Protein)


Gene name relE Uniprot ID A0A0K8M609
Locus tag PsaNZ45_RS22990 Protein ID WP_017684329.1
Coordinates 4746092..4746382 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0K8M645
Locus tag PsaNZ45_RS22985 Protein ID WP_017684328.1
Coordinates 4745857..4746102 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PsaNZ45_RS22980 4741773..4745684 - 3912 WP_020365655.1 ATP-dependent RNA helicase HrpA -
PsaNZ45_RS22985 4745857..4746102 + 246 WP_017684328.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PsaNZ45_RS22990 4746092..4746382 + 291 WP_017684329.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PsaNZ45_RS22995 4746509..4748200 - 1692 WP_003382607.1 long-chain-fatty-acid--CoA ligase FadD1 -
PsaNZ45_RS23000 4748556..4750244 - 1689 WP_017684330.1 long-chain-fatty-acid--CoA ligase FadD2 -
PsaNZ45_RS23010 4750640..4751110 + 471 WP_003382605.1 MaoC family dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11019.86 Da        Isoelectric Point: 10.4180

>T65792 WP_017684329.1 NZ_CP017007:4746092-4746382 [Pseudomonas syringae pv. actinidiae]
MTFKLEFLPSALKEWKKLGHTVSAQLKKKLLERLELPRNAGDALHGMPDHYKIKLRSAGYRLVYRVEDDRVVVTVVAVGK
RERGDIYDSAKDRLSP

Download         Length: 291 bp

>T65792 NZ_CP017007:4746092-4746382 [Pseudomonas syringae pv. actinidiae]
TTGACCTTTAAGCTCGAGTTTCTGCCTTCAGCCCTGAAAGAGTGGAAAAAACTGGGGCATACCGTTAGTGCTCAACTCAA
GAAAAAGCTTTTGGAGCGGCTCGAATTACCTCGAAATGCGGGCGATGCGCTGCATGGCATGCCCGATCACTACAAAATCA
AGTTGCGCAGTGCTGGTTACAGACTGGTTTACCGGGTGGAAGATGATCGGGTAGTAGTGACCGTCGTCGCTGTAGGCAAG
CGCGAACGAGGCGATATCTACGATTCAGCCAAGGACAGGCTGTCTCCCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8860.38 Da        Isoelectric Point: 4.9721

>AT65792 WP_017684328.1 NZ_CP017007:4745857-4746102 [Pseudomonas syringae pv. actinidiae]
MQNIFADIAVSVSELKKNPSAVLSGAQGLPVAVLNHNKVMGYMVPAEVFEAMMKRLDDLDLADLIKARQHEKPVSVDILD
L

Download         Length: 246 bp

>AT65792 NZ_CP017007:4745857-4746102 [Pseudomonas syringae pv. actinidiae]
ATGCAAAATATCTTTGCGGACATCGCGGTCAGCGTCTCTGAACTGAAGAAAAACCCGTCAGCCGTCCTGAGCGGCGCACA
AGGCTTGCCCGTCGCAGTACTCAATCACAATAAAGTCATGGGCTACATGGTGCCTGCCGAGGTGTTTGAAGCAATGATGA
AGCGCCTTGATGACCTCGATCTGGCCGACCTGATCAAAGCCAGGCAACATGAAAAGCCGGTATCGGTAGATATACTTGAC
CTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8M609

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M645

References