Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParST/RES-TIGR02293
Location 1427153..1428138 Replicon chromosome
Accession NZ_CP016949
Organism Cupriavidus taiwanensis strain SWF66294

Toxin (Protein)


Gene name ParT Uniprot ID -
Locus tag A9P79_RS06420 Protein ID WP_115700435.1
Coordinates 1427665..1428138 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name ParS Uniprot ID -
Locus tag A9P79_RS06415 Protein ID WP_240070635.1
Coordinates 1427153..1427668 (+) Length 172 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A9P79_RS06385 (A9P79_06260) 1422574..1423218 + 645 WP_115683015.1 TetR/AcrR family transcriptional regulator -
A9P79_RS06390 (A9P79_06265) 1423561..1423887 + 327 WP_115700422.1 hypothetical protein -
A9P79_RS06395 (A9P79_06270) 1423965..1424147 + 183 WP_240070632.1 hypothetical protein -
A9P79_RS06400 (A9P79_06275) 1424196..1424621 - 426 WP_115700426.1 hypothetical protein -
A9P79_RS06405 (A9P79_06280) 1424864..1425985 - 1122 WP_240070633.1 site-specific integrase -
A9P79_RS06410 (A9P79_06285) 1426100..1427059 + 960 WP_240070634.1 DNA-binding protein -
A9P79_RS06415 (A9P79_06290) 1427153..1427668 + 516 WP_240070635.1 DUF2384 domain-containing protein Antitoxin
A9P79_RS06420 (A9P79_06295) 1427665..1428138 + 474 WP_115700435.1 RES family NAD+ phosphorylase Toxin
A9P79_RS06425 (A9P79_06300) 1428146..1429723 - 1578 WP_240070636.1 fatty acid--CoA ligase -
A9P79_RS06430 (A9P79_06305) 1429904..1432234 + 2331 WP_240070637.1 ATP-dependent DNA helicase -
A9P79_RS06435 (A9P79_06310) 1432359..1432682 + 324 WP_240070638.1 thioredoxin family protein -
A9P79_RS06440 (A9P79_06315) 1432704..1433135 - 432 WP_240070639.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(4-152)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(44-105)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 16629.93 Da        Isoelectric Point: 7.2753

>T65640 WP_115700435.1 NZ_CP016949:1427665-1428138 [Cupriavidus taiwanensis]
MTPAWRIATDTPLYTADDASGAGAKASGGRWNRQGTSLIYAASSIALACLETLVHLGSAGLPLNRYLVRIDIPDDLWAAA
GRLTAASAPVGWDAIPAGKTSLDTGEAWIRAGTSALLLVPSIVIPEEHNVLVNPLHADAGRLAYTKVRRWQYDARLA

Download         Length: 474 bp

>T65640 NZ_CP016949:1427665-1428138 [Cupriavidus taiwanensis]
TTGACGCCGGCGTGGCGCATCGCGACCGACACGCCCCTCTATACCGCGGACGATGCCAGCGGCGCCGGCGCCAAGGCGAG
CGGAGGGCGCTGGAACCGGCAGGGCACGTCCCTGATTTACGCGGCCTCGAGCATTGCGCTGGCGTGCCTGGAAACGCTGG
TTCACCTGGGCTCGGCCGGCCTGCCGTTGAACCGCTACCTGGTCCGCATCGATATTCCCGACGACTTGTGGGCCGCGGCA
GGGCGCTTGACGGCTGCCAGCGCGCCGGTCGGCTGGGATGCCATTCCCGCCGGCAAGACCAGCCTCGATACCGGCGAGGC
GTGGATCCGCGCGGGCACGAGCGCCTTGCTGCTGGTGCCTTCCATCGTGATTCCCGAAGAGCACAACGTGCTGGTCAATC
CCTTGCACGCGGATGCCGGCCGGCTGGCCTATACCAAGGTGCGCCGCTGGCAGTACGACGCACGCCTGGCCTGA

Antitoxin


Download         Length: 172 a.a.        Molecular weight: 18523.07 Da        Isoelectric Point: 8.5129

>AT65640 WP_240070635.1 NZ_CP016949:1427153-1427668 [Cupriavidus taiwanensis]
MPRMLTPEGHYPLAHQRRAARELGVNSYLAVYEATLSTEGAMSVIQAIREGVPASDLNRLAESMGTSKEQLIKTLDLPRA
TVDRKARAHQNLSSEQSERVLGMVRLVGQVQALVESSGDARGFNAAQWVAQWLEQPSPALGGQRPAALMDTVAGQRIVSE
LVARMQSGAYA

Download         Length: 516 bp

>AT65640 NZ_CP016949:1427153-1427668 [Cupriavidus taiwanensis]
ATGCCGCGCATGCTCACGCCTGAAGGCCATTATCCGCTCGCACACCAACGCCGCGCCGCCCGCGAACTCGGCGTCAATAG
CTACCTGGCGGTCTACGAGGCCACGCTGTCGACCGAAGGCGCCATGTCGGTGATCCAAGCCATCCGCGAGGGCGTGCCGG
CTTCCGATCTCAACCGGCTGGCCGAATCGATGGGCACGAGCAAGGAACAGCTGATCAAGACGCTGGATTTGCCGCGTGCC
ACCGTCGACCGCAAGGCGCGCGCCCACCAGAACCTGTCGAGCGAGCAGAGCGAGCGCGTGCTCGGCATGGTGCGGCTGGT
GGGCCAGGTACAGGCGCTGGTGGAAAGCTCGGGCGATGCGCGCGGCTTCAATGCGGCGCAGTGGGTGGCGCAGTGGCTGG
AGCAGCCGTCGCCGGCGCTGGGCGGCCAACGCCCCGCCGCGCTGATGGATACCGTCGCGGGCCAGCGCATCGTCTCCGAG
CTGGTGGCCAGGATGCAGAGCGGGGCCTACGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References