Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 4662585..4663057 Replicon chromosome
Accession NZ_CP016948
Organism Serratia surfactantfaciens strain YD25

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag ATE40_RS21775 Protein ID WP_019452522.1
Coordinates 4662782..4663057 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag ATE40_RS21770 Protein ID WP_019452523.1
Coordinates 4662585..4662782 (+) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATE40_RS21740 4657797..4659065 + 1269 WP_063918199.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
ATE40_RS21745 4659062..4660261 + 1200 WP_019452528.1 anaerobic glycerol-3-phosphate dehydrogenase subunit C -
ATE40_RS21750 4660296..4660841 - 546 WP_063918198.1 DcrB family lipoprotein -
ATE40_RS21755 4660922..4661356 - 435 WP_019452526.1 GNAT family N-acetyltransferase -
ATE40_RS21760 4661398..4662057 - 660 WP_063918197.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
ATE40_RS21765 4662278..4662523 + 246 WP_004934314.1 sulfurtransferase TusA -
ATE40_RS21770 4662585..4662782 + 198 WP_019452523.1 hypothetical protein Antitoxin
ATE40_RS21775 4662782..4663057 + 276 WP_019452522.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
ATE40_RS21780 4663117..4665435 - 2319 WP_063918196.1 zinc/cadmium/mercury/lead-transporting ATPase -
ATE40_RS21785 4666117..4667580 + 1464 WP_019452520.1 serralysin family metalloprotease -
ATE40_RS21790 4667636..4668013 + 378 WP_025160390.1 AprI/Inh family metalloprotease inhibitor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10685.61 Da        Isoelectric Point: 11.5760

>T65637 WP_019452522.1 NZ_CP016948:4662782-4663057 [Serratia surfactantfaciens]
MLNIEWTRSARRDLAEIVGFIANDNPLAARKMKLLIMEAVIPAARHPRLFRRGRVDGTHEIPLHPNYLLVYQVLETHIRV
LRVLHARRQYP

Download         Length: 276 bp

>T65637 NZ_CP016948:4662782-4663057 [Serratia surfactantfaciens]
ATGCTCAACATCGAATGGACTCGATCCGCTCGTCGGGATCTGGCGGAGATTGTGGGATTCATCGCCAATGATAATCCCTT
GGCGGCCAGAAAAATGAAGCTTCTCATCATGGAGGCGGTCATTCCCGCCGCCAGACATCCTCGACTTTTCCGGCGTGGCA
GAGTGGATGGCACGCATGAAATCCCTCTACATCCCAATTATCTCTTGGTTTATCAAGTGCTGGAAACTCACATCCGGGTG
TTGAGGGTTTTACATGCGCGCCGACAATATCCGTAG

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7307.38 Da        Isoelectric Point: 4.1509

>AT65637 WP_019452523.1 NZ_CP016948:4662585-4662782 [Serratia surfactantfaciens]
MSILLLPTVAKMESEERTQGYERWFLESVQEAMDEPLPGIPHDEVMAEMDAVIAAAEARMKAKQS

Download         Length: 198 bp

>AT65637 NZ_CP016948:4662585-4662782 [Serratia surfactantfaciens]
ATGAGTATTTTACTACTGCCAACGGTTGCCAAGATGGAAAGTGAGGAACGTACACAGGGCTATGAGCGCTGGTTTCTTGA
GAGCGTTCAGGAAGCCATGGATGAGCCGCTGCCCGGTATTCCTCATGACGAGGTGATGGCTGAAATGGATGCGGTTATCG
CTGCTGCAGAAGCCAGGATGAAAGCTAAGCAGTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References