Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 4116667..4117259 Replicon chromosome
Accession NZ_CP016948
Organism Serratia surfactantfaciens strain YD25

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag ATE40_RS19345 Protein ID WP_019456151.1
Coordinates 4116909..4117259 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag ATE40_RS19340 Protein ID WP_025159908.1
Coordinates 4116667..4116915 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ATE40_RS19315 4112276..4112473 + 198 WP_063918403.1 hypothetical protein -
ATE40_RS19320 4112487..4112825 + 339 WP_019456147.1 PTS lactose/cellobiose transporter subunit IIA -
ATE40_RS19325 4112822..4114129 + 1308 WP_019456148.1 6-phospho-beta-glucosidase -
ATE40_RS19330 4114203..4115183 + 981 WP_063918402.1 LacI family transcriptional regulator -
ATE40_RS19335 4115372..4116556 + 1185 WP_004930336.1 MFS transporter TsgA -
ATE40_RS19340 4116667..4116915 + 249 WP_025159908.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
ATE40_RS19345 4116909..4117259 + 351 WP_019456151.1 type II toxin-antitoxin system ChpB family toxin Toxin
ATE40_RS19350 4117256..4118539 - 1284 WP_063918401.1 cytosine deaminase -
ATE40_RS19360 4118828..4121377 + 2550 WP_063918400.1 nitrite reductase large subunit NirB -
ATE40_RS19365 4121374..4121700 + 327 WP_019456155.1 nitrite reductase small subunit NirD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(8-114)

Antitoxin

Antitoxin PemI-like

(1-82)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12371.34 Da        Isoelectric Point: 11.0634

>T65635 WP_019456151.1 NZ_CP016948:4116909-4117259 [Serratia surfactantfaciens]
MVKRPVFQRGDLIRVSLNPVVGREQQGDFRPALVLSPREFNALGMVLVAPISQGANFARTAGFTVSLSGSGTATQGVILI
NQVRMMDLAGRSAQFVEHAPGEVIADALARLQAIID

Download         Length: 351 bp

>T65635 NZ_CP016948:4116909-4117259 [Serratia surfactantfaciens]
ATGGTGAAGCGCCCCGTTTTTCAGCGCGGAGATCTTATCCGGGTCAGCCTGAATCCCGTGGTTGGCCGTGAGCAACAAGG
CGACTTTCGTCCGGCACTGGTGCTGTCTCCCCGCGAGTTCAATGCGCTGGGCATGGTATTGGTCGCCCCCATTTCCCAAG
GGGCGAATTTTGCCCGTACAGCGGGTTTCACCGTCAGCCTGAGCGGCAGTGGCACCGCAACGCAGGGCGTCATCTTGATC
AATCAGGTTCGCATGATGGATCTGGCCGGGCGCAGCGCGCAATTCGTCGAGCATGCCCCCGGCGAAGTCATCGCCGATGC
ACTGGCGCGGCTTCAGGCGATCATCGACTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8982.41 Da        Isoelectric Point: 4.5026

>AT65635 WP_025159908.1 NZ_CP016948:4116667-4116915 [Serratia surfactantfaciens]
MKVSIKKWGNSAGMLVPSALMNELELQVGQEMDMQVIDGALVIKPVKKRYSLQQLLDGCDGEAPAAADDSWEHMPPAGKE
VW

Download         Length: 249 bp

>AT65635 NZ_CP016948:4116667-4116915 [Serratia surfactantfaciens]
ATGAAAGTCTCTATCAAAAAATGGGGCAACAGCGCGGGAATGCTGGTGCCCTCAGCGCTAATGAACGAGCTGGAACTACA
GGTAGGTCAGGAAATGGACATGCAGGTTATCGATGGAGCGTTGGTCATTAAGCCGGTTAAGAAACGCTATTCACTGCAGC
AATTGCTCGATGGCTGCGACGGTGAAGCGCCGGCCGCCGCAGACGACAGCTGGGAACACATGCCGCCGGCGGGGAAAGAA
GTATGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References