Detailed information of TA system TA065498

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 3555296..3555974
• Replicon: chromosome
• Accession: NZ_CP016928
• Organism: Dickeya solani RNS 08.23.3.1.A

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: D083_RS15665
• Protein ID: WP_023637601.1
• Coordinates: 3555543..3555974 (+)
• Length: 144 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A2K8QSU7
• Locus tag: D083_RS15660
• Protein ID: WP_023637600.1
• Coordinates: 3555296..3555562 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
D083_RS15640	3551746..3552396	+	651	WP_022632163.1	LysE family translocator	-
D083_RS15645	3552467..3553075	-	609	WP_022632164.1	HD domain-containing protein	-
D083_RS15650	3553285..3553935	+	651	WP_022632165.1	hemolysin III family protein	-
D083_RS15655	3554009..3554989	-	981	WP_022632166.1	tRNA-modifying protein YgfZ	-
D083_RS15660	3555296..3555562	+	267	WP_023637600.1	FAD assembly factor SdhE	Antitoxin
D083_RS15665	3555543..3555974	+	432	WP_023637601.1	protein YgfX	Toxin
D083_RS15670	3556074..3556592	-	519	WP_022632169.1	flavodoxin FldB	-
D083_RS15675	3556721..3558046	-	1326	WP_022632170.1	MHS family MFS transporter	-
D083_RS15680	3558309..3559208	+	900	WP_022632171.1	site-specific tyrosine recombinase XerD	-
D083_RS15685	3559298..3560005	+	708	WP_022632172.1	bifunctional protein-disulfide isomerase/oxidoreductase DsbC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 144 a.a.
• Molecular weight: 16808.51 Da
• Isoelectric Point: 11.7737

>T65498 WP_023637601.1 NZ_CP016928:3555543-3555974 [Dickeya solani RNS 08.23.3.1.A]
VAQWQCDLRVSWRMQLFSLLTHGFLVLMILLAPWPDGYAPLWLGLVTLVVFGFVRSQRIIKSRQGEISLHGENQLHWQQR
DWQIARRPWVMRNGVLLSLRATTGKGHQRLWLASDSMGNEEWRLLRQLLQQHPLQGTESSRHH

Nucleotide

• Length: 432 bp

>T65498 NZ_CP016928:3555543-3555974 [Dickeya solani RNS 08.23.3.1.A]
GTGGCCCAGTGGCAATGTGATTTACGCGTATCCTGGCGCATGCAGTTGTTTTCGCTGCTGACGCACGGGTTTCTGGTGCT
GATGATCCTGCTGGCGCCCTGGCCGGACGGCTATGCGCCGCTGTGGCTGGGGTTGGTGACGCTGGTGGTGTTCGGTTTCG
TGCGCAGTCAGCGCATCATTAAGTCGCGTCAGGGGGAAATTTCCCTGCATGGGGAAAACCAACTGCACTGGCAGCAGCGT
GACTGGCAGATAGCCCGGCGACCGTGGGTGATGCGCAACGGCGTGTTGCTGTCGTTGCGGGCGACGACTGGCAAAGGGCA
TCAGCGTCTGTGGCTGGCGTCAGACAGTATGGGCAATGAAGAGTGGCGGCTGTTGCGCCAGCTGTTGCAGCAGCACCCGC
TGCAGGGAACGGAATCTTCCCGCCATCATTAA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10544.03 Da
• Isoelectric Point: 5.5535

>AT65498 WP_023637600.1 NZ_CP016928:3555296-3555562 [Dickeya solani RNS 08.23.3.1.A]
MDINNKSRIHWACRRGMRELDISIMPFFEHEYDTLSDDDKQHFIRLLQCDDPDLFNWLMNHGEPVDPELKRMVSLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT65498 NZ_CP016928:3555296-3555562 [Dickeya solani RNS 08.23.3.1.A]
ATGGACATCAATAACAAATCACGTATTCACTGGGCGTGCAGACGCGGAATGCGTGAACTGGATATCTCCATCATGCCGTT
TTTCGAGCATGAGTACGACACGCTGAGCGACGACGACAAGCAGCATTTCATCCGTCTGTTGCAGTGCGACGATCCCGACT
TGTTCAACTGGCTGATGAACCATGGCGAGCCGGTGGATCCGGAGCTGAAACGTATGGTTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCAATGTGA

Structures

Antitoxin

• AlphaFold DB: A0A2K8QSU7