Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 4593174..4593319 | Replicon | chromosome |
| Accession | NZ_CP016926 | ||
| Organism | Klebsiella pneumoniae isolate 23 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 4593210..4593312 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 4593174..4593319 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A8C23_RS23415 | 4588304..4590364 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| A8C23_RS23420 | 4590368..4591027 | - | 660 | WP_004180433.1 | exodeoxyribonuclease X | - |
| A8C23_RS23425 | 4591106..4591336 | - | 231 | WP_032422712.1 | DNA polymerase III subunit theta | - |
| A8C23_RS23430 | 4591449..4591823 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| A8C23_RS23435 | 4591827..4592696 | + | 870 | WP_004151447.1 | copper homeostasis membrane protein CopD | - |
| A8C23_RS23440 | 4592713..4593051 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 4593174..4593319 | - | 146 | - | - | Antitoxin |
| - | 4593210..4593312 | + | 103 | - | - | Toxin |
| A8C23_RS30030 | 4593688..4593831 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| A8C23_RS23450 | 4593936..4594904 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| A8C23_RS23455 | 4595061..4595714 | + | 654 | WP_004180432.1 | protein-serine/threonine phosphatase | - |
| A8C23_RS23460 | 4595711..4595902 | - | 192 | WP_002911395.1 | YebW family protein | - |
| A8C23_RS23465 | 4596000..4596239 | - | 240 | WP_002911393.1 | YebV family protein | - |
| A8C23_RS23470 | 4596355..4597788 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T65476 NZ_CP016926:4593210-4593312 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT65476 NZ_CP016926:c4593319-4593174 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
