Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4032940..4033085 Replicon chromosome
Accession NZ_CP016923
Organism Klebsiella pneumoniae isolate 11

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4032976..4033078 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4032940..4033085 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8C11_RS21830 4028070..4030130 + 2061 WP_004151449.1 oligopeptidase B -
A8C11_RS21835 4030134..4030793 - 660 WP_043906809.1 exodeoxyribonuclease X -
A8C11_RS21840 4030872..4031102 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A8C11_RS21845 4031215..4031589 + 375 WP_004151448.1 CopC domain-containing protein YobA -
A8C11_RS21850 4031593..4032462 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
A8C11_RS21855 4032479..4032817 + 339 WP_002911404.1 YebY family protein -
- 4032940..4033085 - 146 - - Antitoxin
- 4032976..4033078 + 103 - - Toxin
A8C11_RS32060 4033454..4033597 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
A8C11_RS21865 4033702..4034670 - 969 WP_004151446.1 VirK/YbjX family protein -
A8C11_RS21870 4034827..4035480 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
A8C11_RS21875 4035477..4035668 - 192 WP_002911395.1 YebW family protein -
A8C11_RS21880 4035766..4036005 - 240 WP_002911393.1 YebV family protein -
A8C11_RS21885 4036121..4037554 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T65457 NZ_CP016923:4032976-4033078 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT65457 NZ_CP016923:c4033085-4032940 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References