Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 520274..520935 Replicon chromosome
Accession NZ_CP016914
Organism Ralstonia solanacearum strain CQPS-1

Toxin (Protein)


Gene name vapC Uniprot ID A0A9E7Z845
Locus tag BC350_RS02485 Protein ID WP_016727753.1
Coordinates 520522..520935 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A9E7Z6P3
Locus tag BC350_RS02480 Protein ID WP_019717749.1
Coordinates 520274..520525 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BC350_RS02460 515923..516639 + 717 WP_049800424.1 Crp/Fnr family transcriptional regulator -
BC350_RS27125 517314..517652 - 339 WP_016727784.1 glycine zipper 2TM domain-containing protein -
BC350_RS26280 517926..518141 + 216 WP_071615547.1 hypothetical protein -
BC350_RS02470 518295..518527 - 233 Protein_478 hypothetical protein -
BC350_RS02475 519124..519999 + 876 WP_049800423.1 hypothetical protein -
BC350_RS02480 520274..520525 + 252 WP_019717749.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
BC350_RS02485 520522..520935 + 414 WP_016727753.1 type II toxin-antitoxin system VapC family toxin Toxin
BC350_RS02490 521007..522029 - 1023 WP_020425162.1 DNA cytosine methyltransferase -
BC350_RS02495 522652..522939 + 288 WP_089190399.1 H-NS histone family protein -
BC350_RS02500 522982..523626 - 645 WP_089190400.1 hypothetical protein -
BC350_RS02505 523601..523822 - 222 WP_089190401.1 hypothetical protein -
BC350_RS02510 523819..524208 - 390 WP_089190402.1 hypothetical protein -
BC350_RS02515 524369..525616 + 1248 WP_081365215.1 tyrosine-type recombinase/integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15586.89 Da        Isoelectric Point: 6.2337

>T65439 WP_016727753.1 NZ_CP016914:520522-520935 [Ralstonia solanacearum]
MSYLIDTNVLSELRRKAPDARVVAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLEVELPNYFLGRLLDID
AHTADRWGRLMSSAGRPLPAIDGLLAATALQHDLTLVTRNTKDFAGLDVQLINPWEA

Download         Length: 414 bp

>T65439 NZ_CP016914:520522-520935 [Ralstonia solanacearum]
TTGAGTTACCTGATCGACACCAATGTCCTGTCCGAATTGCGCCGCAAAGCGCCCGATGCGCGCGTGGTGGCCTGGATGCA
GGACCGCCCGCGCCAGTCGCTCTACCTGAGCGTGCTGACCCTGGGCGAGATTCGCAAAGGTATCGAGCGGCTGGACGACG
CGGCGCGCCGCCAGCACCTGATTGACTGGCTCGAAGTGGAACTGCCGAACTACTTTCTCGGCCGATTGCTCGACATCGAT
GCGCATACCGCCGACCGCTGGGGCCGGCTGATGTCCTCGGCCGGCCGCCCCCTGCCCGCCATCGACGGCCTGCTGGCCGC
GACCGCCCTGCAACACGACCTCACGCTGGTCACGCGCAACACCAAGGATTTCGCGGGGCTCGACGTCCAGCTCATCAACC
CATGGGAAGCCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9305.49 Da        Isoelectric Point: 5.0774

>AT65439 WP_019717749.1 NZ_CP016914:520274-520525 [Ralstonia solanacearum]
MQSWQMQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGGGESLVSFMRQSPLADQDDVVFERERSLPRE
VEF

Download         Length: 252 bp

>AT65439 NZ_CP016914:520274-520525 [Ralstonia solanacearum]
ATGCAAAGCTGGCAAATGCAGGCCGCCAAGGCGCGGTTTTCCGATGTCGTGAAGCGGGCGGCAGACGATGGCCCGCAGGA
AATCACCGTGCATGGCCGCCCGGTGGCGGTGGTGATCTCGCGCGCACTGTTCGATCGCTTGAGCGGCGGCGGTGAGTCGC
TGGTCAGCTTCATGCGCCAATCCCCGCTGGCCGACCAGGACGATGTCGTCTTTGAGCGCGAGCGCAGCCTGCCGCGCGAG
GTCGAGTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References