Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 1089751..1090280 Replicon plasmid unnamed1
Accession NZ_CP016905
Organism Ralstonia solanacearum strain KACC 10709

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LBM341_RS20375 Protein ID WP_016722340.1
Coordinates 1090053..1090280 (-) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LBM341_RS20370 Protein ID WP_016722339.1
Coordinates 1089751..1090056 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LBM341_RS20350 1084945..1085769 - 825 Protein_881 GGDEF domain-containing protein -
LBM341_RS20355 1085891..1086847 + 957 WP_069078857.1 IS5-like element IS1420 family transposase -
LBM341_RS25500 1087068..1087285 + 218 Protein_883 transposase -
LBM341_RS20360 1087452..1088120 + 669 WP_038938024.1 hypothetical protein -
LBM341_RS20365 1088225..1089538 - 1314 WP_038938025.1 metabolite/H+ symporter -
LBM341_RS20370 1089751..1090056 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
LBM341_RS20375 1090053..1090280 - 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LBM341_RS20380 1090435..1091634 - 1200 WP_016726513.1 MFS transporter -
LBM341_RS20385 1091761..1092582 - 822 WP_011003398.1 GntR family transcriptional regulator -
LBM341_RS20390 1092760..1093311 - 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
LBM341_RS20395 1093444..1094043 + 600 WP_016722344.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - acrB / cheY / cheB / cheW / motA / cyaB / flgC / flgG / fliM / fliG / fliI / adeG 1..2145732 2145732
- flank IS/Tn - - 1085993..1086847 854


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T65423 WP_016722340.1 NZ_CP016905:c1090280-1090053 [Ralstonia solanacearum]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T65423 NZ_CP016905:c1090280-1090053 [Ralstonia solanacearum]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT65423 WP_016722339.1 NZ_CP016905:c1090056-1089751 [Ralstonia solanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT65423 NZ_CP016905:c1090056-1089751 [Ralstonia solanacearum]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References