Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3012460..3013121 Replicon chromosome
Accession NZ_CP016904
Organism Ralstonia solanacearum strain KACC 10709

Toxin (Protein)


Gene name vapC Uniprot ID A0A9E7Z845
Locus tag LBM341_RS14020 Protein ID WP_016727753.1
Coordinates 3012708..3013121 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A9E7Z6P3
Locus tag LBM341_RS14015 Protein ID WP_019717749.1
Coordinates 3012460..3012711 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LBM341_RS25780 3008147..3008296 - 150 WP_155738951.1 hypothetical protein -
LBM341_RS14000 3008293..3009258 - 966 WP_016721735.1 IS5 family transposase -
LBM341_RS24730 3009263..3009640 - 378 WP_081326686.1 AAA family ATPase -
LBM341_RS14005 3009682..3010638 - 957 WP_069078857.1 IS5-like element IS1420 family transposase -
LBM341_RS25785 3010746..3011501 + 756 WP_157774208.1 hypothetical protein -
LBM341_RS25425 3011670..3011801 - 132 Protein_2794 IS5/IS1182 family transposase -
LBM341_RS14010 3011850..3012083 - 234 WP_081326699.1 hypothetical protein -
LBM341_RS24735 3012108..3012380 - 273 Protein_2796 hypothetical protein -
LBM341_RS14015 3012460..3012711 + 252 WP_019717749.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
LBM341_RS14020 3012708..3013121 + 414 WP_016727753.1 type II toxin-antitoxin system VapC family toxin Toxin
LBM341_RS14025 3013193..3014215 - 1023 WP_081326687.1 DNA cytosine methyltransferase -
LBM341_RS14030 3014839..3015126 + 288 WP_019717747.1 H-NS histone family protein -
LBM341_RS14035 3015169..3015813 - 645 WP_069079212.1 hypothetical protein -
LBM341_RS14040 3015788..3016009 - 222 WP_069079338.1 hypothetical protein -
LBM341_RS14045 3016006..3016401 - 396 WP_069079213.1 hypothetical protein -
LBM341_RS14050 3016410..3017183 - 774 WP_069079214.1 hypothetical protein -
LBM341_RS14055 3017306..3017752 - 447 WP_069079215.1 hypothetical protein -
LBM341_RS14060 3017758..3018060 - 303 WP_069079216.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3002412..3054584 52172


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15586.89 Da        Isoelectric Point: 6.2337

>T65422 WP_016727753.1 NZ_CP016904:3012708-3013121 [Ralstonia solanacearum]
MSYLIDTNVLSELRRKAPDARVVAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLEVELPNYFLGRLLDID
AHTADRWGRLMSSAGRPLPAIDGLLAATALQHDLTLVTRNTKDFAGLDVQLINPWEA

Download         Length: 414 bp

>T65422 NZ_CP016904:3012708-3013121 [Ralstonia solanacearum]
TTGAGTTACCTGATCGACACCAATGTCCTGTCCGAATTGCGCCGCAAAGCGCCCGATGCGCGCGTGGTGGCCTGGATGCA
GGACCGCCCGCGCCAGTCGCTCTACCTGAGCGTGCTGACCCTGGGCGAGATTCGCAAAGGTATCGAGCGGCTGGACGACG
CGGCGCGCCGCCAGCACCTGATTGACTGGCTCGAAGTGGAACTGCCGAACTACTTTCTCGGCCGATTGCTCGACATCGAT
GCGCATACCGCCGACCGCTGGGGCCGGCTGATGTCCTCGGCCGGCCGCCCCCTGCCCGCCATCGACGGCCTGCTGGCCGC
GACCGCCCTGCAACACGACCTCACGCTGGTCACGCGCAACACCAAGGATTTCGCGGGGCTCGACGTCCAGCTCATCAACC
CATGGGAAGCCTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9305.49 Da        Isoelectric Point: 5.0774

>AT65422 WP_019717749.1 NZ_CP016904:3012460-3012711 [Ralstonia solanacearum]
MQSWQMQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGGGESLVSFMRQSPLADQDDVVFERERSLPRE
VEF

Download         Length: 252 bp

>AT65422 NZ_CP016904:3012460-3012711 [Ralstonia solanacearum]
ATGCAAAGCTGGCAAATGCAGGCCGCCAAGGCGCGGTTTTCCGATGTCGTGAAGCGGGCGGCAGACGATGGCCCGCAGGA
AATCACCGTGCATGGCCGCCCGGTGGCGGTGGTGATCTCGCGCGCACTGTTCGATCGCTTGAGCGGCGGCGGTGAGTCGC
TGGTCAGCTTCATGCGCCAATCCCCGCTGGCCGACCAGGACGATGTCGTCTTTGAGCGCGAGCGCAGCCTGCCGCGCGAG
GTCGAGTTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References