Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 495530..496440 Replicon plasmid unnamed1
Accession NZ_CP016890
Organism Pantoea agglomerans strain C410P1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag BEE12_RS21580 Protein ID WP_069026891.1
Coordinates 495530..496000 (-) Length 157 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag BEE12_RS21585 Protein ID WP_064703869.1
Coordinates 495997..496440 (-) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BEE12_RS21570 491609..494338 + 2730 WP_069026890.1 cation-transporting P-type ATPase -
BEE12_RS21575 494327..495358 - 1032 WP_031594315.1 AI-2E family transporter -
BEE12_RS21580 495530..496000 - 471 WP_069026891.1 RES family NAD+ phosphorylase Toxin
BEE12_RS21585 495997..496440 - 444 WP_064703869.1 DUF2384 domain-containing protein Antitoxin
BEE12_RS21590 496585..496842 + 258 Protein_458 aldo/keto reductase -
BEE12_RS24300 496877..497294 - 418 Protein_459 hypothetical protein -
BEE12_RS21595 497508..498122 + 615 WP_069026893.1 TetR/AcrR family transcriptional regulator -
BEE12_RS21600 498173..499072 + 900 WP_064703866.1 alpha/beta hydrolase -
BEE12_RS21605 499314..500501 + 1188 WP_069026894.1 amidohydrolase -
BEE12_RS21610 500523..501371 + 849 WP_022624593.1 transporter substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - iroN 1..543504 543504


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-148)

Antitoxin

Antitoxin Xre

(16-147)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17466.90 Da        Isoelectric Point: 4.7699

>T65402 WP_069026891.1 NZ_CP016890:c496000-495530 [Pantoea agglomerans]
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKPDRK

Download         Length: 471 bp

>T65402 NZ_CP016890:c496000-495530 [Pantoea agglomerans]
TTGATTCTCTACAGGCTGACCAAGACAAAGTATCTTTCGACAGCCTGGACGGGATTTGGCGCAAAAGAGGCGGGCGGCCG
CTGGAACAGCATCGGCATCTCCATGGTTTATGTTTCTGAAACAGCATCGCTGACTTTGCTGGAAACACTGGTCCATCTGC
ACTCAGCACACATCCTGGACGCGTTCACACTTCTGCGCATCGATGTTCCCGATGCGCTGATTCAGACCGCTGATATCACT
GAGTTGCCTGCAAACTGGGCCGATGAAGACGCACCGGCAGAACTGGCTGACTATGGAGACGCCTGGTGCTCTGCCTGCGA
TGCGGTTGCGTTGCGTGTTCCCAGTGCCCTCTCCCCTGTAGAATATAACTATCTGTTAAATCCTGAACACCCCGATTTCT
TCCGTATAGTTCAACAGGCTGAGGCTATTCCGTTCCGGTTTGATCGTCGGCTGAAACCGGATCGTAAATAA

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16463.84 Da        Isoelectric Point: 9.9250

>AT65402 WP_064703869.1 NZ_CP016890:c496440-495997 [Pantoea agglomerans]
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS

Download         Length: 444 bp

>AT65402 NZ_CP016890:c496440-495997 [Pantoea agglomerans]
ATGAAAACATTCAGCTTTTCTGCGAATAAAACCAGGGCGCCACGCTTATGGCAGGCCGCAGGCCTGAACAACGCTGATGG
TGTCGCCCTGCTGGGCCAGATTAATGAAGGCCTTGATGGCAACGTAGCTCACCTGATCGTCAACTGGGCGAAGATTACGC
AAAACGATCTGCGCAAAATGTCCGGTATTCCCTCCACGACGTTCAGCCGGAGCGTGAAAGCGAAATTCAGCGCTGAACAA
AGTGAACGACTGGTACGAATTATCCGTGTCATTGATCGCGCAGTTGAACTGTTCGAAGGTGATAAGGATGAAGCGCAAAA
ATGGTTGAATGAGCCTAACAGGGCGCTGAGCTGGAAAATGCCCGCAGAACTGATGGCGTCTGAAACCGGGGCATACGAGG
TCATGAAATTAATCACGCGCCTGGAGCACGGAGTTTACTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References