Detailed information of TA system TA065402

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 495530..496440
• Replicon: plasmid unnamed1
• Accession: NZ_CP016890
• Organism: Pantoea agglomerans strain C410P1

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BEE12_RS21580
• Protein ID: WP_069026891.1
• Coordinates: 495530..496000 (-)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: BEE12_RS21585
• Protein ID: WP_064703869.1
• Coordinates: 495997..496440 (-)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BEE12_RS21570	491609..494338	+	2730	WP_069026890.1	cation-transporting P-type ATPase	-
BEE12_RS21575	494327..495358	-	1032	WP_031594315.1	AI-2E family transporter	-
BEE12_RS21580	495530..496000	-	471	WP_069026891.1	RES family NAD+ phosphorylase	Toxin
BEE12_RS21585	495997..496440	-	444	WP_064703869.1	DUF2384 domain-containing protein	Antitoxin
BEE12_RS21590	496585..496842	+	258	Protein_458	aldo/keto reductase	-
BEE12_RS24300	496877..497294	-	418	Protein_459	hypothetical protein	-
BEE12_RS21595	497508..498122	+	615	WP_069026893.1	TetR/AcrR family transcriptional regulator	-
BEE12_RS21600	498173..499072	+	900	WP_064703866.1	alpha/beta hydrolase	-
BEE12_RS21605	499314..500501	+	1188	WP_069026894.1	amidohydrolase	-
BEE12_RS21610	500523..501371	+	849	WP_022624593.1	transporter substrate-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	iroN	1..543504	543504

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre (16-147)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 17466.90 Da
• Isoelectric Point: 4.7699

>T65402 WP_069026891.1 NZ_CP016890:c496000-495530 [Pantoea agglomerans]
MILYRLTKTKYLSTAWTGFGAKEAGGRWNSIGISMVYVSETASLTLLETLVHLHSAHILDAFTLLRIDVPDALIQTADIT
ELPANWADEDAPAELADYGDAWCSACDAVALRVPSALSPVEYNYLLNPEHPDFFRIVQQAEAIPFRFDRRLKPDRK

Nucleotide

• Length: 471 bp

>T65402 NZ_CP016890:c496000-495530 [Pantoea agglomerans]
TTGATTCTCTACAGGCTGACCAAGACAAAGTATCTTTCGACAGCCTGGACGGGATTTGGCGCAAAAGAGGCGGGCGGCCG
CTGGAACAGCATCGGCATCTCCATGGTTTATGTTTCTGAAACAGCATCGCTGACTTTGCTGGAAACACTGGTCCATCTGC
ACTCAGCACACATCCTGGACGCGTTCACACTTCTGCGCATCGATGTTCCCGATGCGCTGATTCAGACCGCTGATATCACT
GAGTTGCCTGCAAACTGGGCCGATGAAGACGCACCGGCAGAACTGGCTGACTATGGAGACGCCTGGTGCTCTGCCTGCGA
TGCGGTTGCGTTGCGTGTTCCCAGTGCCCTCTCCCCTGTAGAATATAACTATCTGTTAAATCCTGAACACCCCGATTTCT
TCCGTATAGTTCAACAGGCTGAGGCTATTCCGTTCCGGTTTGATCGTCGGCTGAAACCGGATCGTAAATAA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16463.84 Da
• Isoelectric Point: 9.9250

>AT65402 WP_064703869.1 NZ_CP016890:c496440-495997 [Pantoea agglomerans]
MKTFSFSANKTRAPRLWQAAGLNNADGVALLGQINEGLDGNVAHLIVNWAKITQNDLRKMSGIPSTTFSRSVKAKFSAEQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALSWKMPAELMASETGAYEVMKLITRLEHGVYS

Nucleotide

• Length: 444 bp

>AT65402 NZ_CP016890:c496440-495997 [Pantoea agglomerans]
ATGAAAACATTCAGCTTTTCTGCGAATAAAACCAGGGCGCCACGCTTATGGCAGGCCGCAGGCCTGAACAACGCTGATGG
TGTCGCCCTGCTGGGCCAGATTAATGAAGGCCTTGATGGCAACGTAGCTCACCTGATCGTCAACTGGGCGAAGATTACGC
AAAACGATCTGCGCAAAATGTCCGGTATTCCCTCCACGACGTTCAGCCGGAGCGTGAAAGCGAAATTCAGCGCTGAACAA
AGTGAACGACTGGTACGAATTATCCGTGTCATTGATCGCGCAGTTGAACTGTTCGAAGGTGATAAGGATGAAGCGCAAAA
ATGGTTGAATGAGCCTAACAGGGCGCTGAGCTGGAAAATGCCCGCAGAACTGATGGCGTCTGAAACCGGGGCATACGAGG
TCATGAAATTAATCACGCGCCTGGAGCACGGAGTTTACTCTTGA