65331

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3148610..3148975 Replicon chromosome
Accession NZ_CP016878
Organism Xanthomonas hortorum strain B07-007

Toxin (Protein)


Gene name EcnB Uniprot ID A0A6V7C9X4
Locus tag XJ27_RS14480 Protein ID WP_074056472.1
Coordinates 3148610..3148744 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID V7Z8F2
Locus tag XJ27_RS14485 Protein ID WP_006451340.1
Coordinates 3148823..3148975 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XJ27_RS14465 3145544..3146488 - 945 WP_095575004.1 MBL fold metallo-hydrolase -
XJ27_RS14470 3146696..3147985 - 1290 WP_074056473.1 tryptophan--tRNA ligase -
XJ27_RS14475 3148159..3148368 - 210 WP_006451342.1 CsbD family protein -
XJ27_RS14480 3148610..3148744 - 135 WP_074056472.1 entericidin A/B family lipoprotein Toxin
XJ27_RS14485 3148823..3148975 - 153 WP_006451340.1 entericidin A/B family lipoprotein Antitoxin
XJ27_RS14490 3149085..3150008 - 924 WP_095575354.1 arginase -
XJ27_RS14495 3150470..3150922 + 453 WP_006452080.1 roadblock/LC7 domain-containing protein -
XJ27_RS14500 3150986..3151345 + 360 WP_006452081.1 hypothetical protein -
XJ27_RS14505 3151439..3152356 + 918 WP_074056471.1 hypothetical protein -
XJ27_RS14510 3152353..3152895 + 543 WP_074056470.1 GTPase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4475.31 Da        Isoelectric Point: 9.3487

>T65331 WP_074056472.1 NZ_CP016878:c3148744-3148610 [Xanthomonas hortorum]
MKRAIILLVLSVFSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T65331 NZ_CP016878:c3148744-3148610 [Xanthomonas hortorum]
ATGAAGCGTGCAATTATACTGCTGGTGCTGTCGGTGTTTTCGGTCGGTATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGCAGGGCGCTGGCGAGAAAGTGGAAGACGCTGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5168.11 Da        Isoelectric Point: 8.2782

>AT65331 WP_006451340.1 NZ_CP016878:c3148975-3148823 [Xanthomonas hortorum]
MKRLLTLMVLGLFSAGVMTGCNTMAGAGKDMQGAGEKVEKKADNCSDGKC

Download         Length: 153 bp

>AT65331 NZ_CP016878:c3148975-3148823 [Xanthomonas hortorum]
ATGAAGCGACTGCTGACACTGATGGTGCTAGGCCTGTTTTCGGCTGGCGTGATGACTGGCTGCAACACCATGGCCGGCGC
CGGCAAGGACATGCAGGGCGCAGGTGAGAAGGTCGAAAAGAAGGCCGATAATTGCAGCGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7C9X4

Antitoxin

Source ID Structure
AlphaFold DB A0A2N7V051

References