Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2234893..2235398 Replicon chromosome
Accession NZ_CP016878
Organism Xanthomonas hortorum strain B07-007

Toxin (Protein)


Gene name relE Uniprot ID A0A6V7D3A5
Locus tag XJ27_RS10025 Protein ID WP_074056859.1
Coordinates 2235141..2235398 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID F0BZS9
Locus tag XJ27_RS10020 Protein ID WP_006448404.1
Coordinates 2234893..2235144 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XJ27_RS10000 2230264..2231418 - 1155 WP_074056862.1 2-methylcitrate synthase -
XJ27_RS10005 2231494..2232390 - 897 WP_074056861.1 methylisocitrate lyase -
XJ27_RS10010 2232519..2234138 + 1620 WP_174555969.1 propionate catabolism operon regulatory protein PrpR -
XJ27_RS10015 2234381..2234707 - 327 WP_074056860.1 hypothetical protein -
XJ27_RS10020 2234893..2235144 + 252 WP_006448404.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
XJ27_RS10025 2235141..2235398 + 258 WP_074056859.1 Txe/YoeB family addiction module toxin Toxin
XJ27_RS10035 2235913..2236266 - 354 WP_003483889.1 PilZ domain-containing protein -
XJ27_RS10040 2236263..2237222 - 960 WP_006448409.1 DNA polymerase III subunit delta' -
XJ27_RS10045 2237219..2238328 - 1110 WP_074056858.1 endolytic transglycosylase MltG -
XJ27_RS10050 2238344..2239699 - 1356 WP_074056857.1 aminodeoxychorismate synthase component I -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10156.66 Da        Isoelectric Point: 9.6587

>T65330 WP_074056859.1 NZ_CP016878:2235141-2235398 [Xanthomonas hortorum]
VILQFADNAWEDYLYWQQTDKKMLKRINELIKAIQRDPFQGIGKPEPLRHALAGYWSRRINDEHRIVYKAENGILLIAQA
RYHYG

Download         Length: 258 bp

>T65330 NZ_CP016878:2235141-2235398 [Xanthomonas hortorum]
GTGATTCTGCAGTTTGCTGACAATGCCTGGGAGGACTACCTCTACTGGCAACAGACCGACAAGAAGATGCTCAAACGCAT
CAACGAGTTGATCAAGGCCATTCAGCGCGATCCTTTCCAGGGCATCGGCAAACCCGAACCGTTGCGCCATGCGCTGGCGG
GCTACTGGTCACGCCGCATCAACGACGAACACCGGATCGTTTACAAGGCCGAGAACGGCATCCTGTTGATTGCTCAGGCG
CGCTACCACTACGGGTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9255.48 Da        Isoelectric Point: 4.6536

>AT65330 WP_006448404.1 NZ_CP016878:2234893-2235144 [Xanthomonas hortorum]
MDTITYSAARASLADTMDRVVNDHEPVIITRSGERAVVMVSLEDYKAMEETAYLLRSPKSAQRLLESIAQLEAGRGKERE
LAE

Download         Length: 252 bp

>AT65330 NZ_CP016878:2234893-2235144 [Xanthomonas hortorum]
ATGGACACCATCACCTACAGCGCCGCGCGTGCCTCTCTGGCCGACACCATGGACCGTGTCGTCAATGACCACGAGCCGGT
GATCATCACGCGCAGCGGTGAGCGCGCCGTGGTCATGGTGTCGCTGGAAGATTACAAGGCCATGGAAGAGACCGCCTACC
TGTTGCGCAGCCCGAAGAGTGCGCAACGGCTGCTGGAATCCATTGCCCAGCTTGAGGCCGGTCGCGGCAAGGAACGGGAA
CTGGCTGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6V7D3A5

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8MAJ7

References