Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 2090..2640 Replicon plasmid pFap29-2
Accession NZ_CP016835
Organism Xanthomonas fragariae isolate Fap29

Toxin (Protein)


Gene name parE Uniprot ID A0A1Y6HCU7
Locus tag BER93_RS19570 Protein ID WP_002804295.1
Coordinates 2090..2374 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HDJ6
Locus tag BER93_RS19575 Protein ID WP_002804296.1
Coordinates 2362..2640 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BER93_RS19565 1722..1904 + 183 WP_134656646.1 hypothetical protein -
BER93_RS19570 2090..2374 - 285 WP_002804295.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BER93_RS19575 2362..2640 - 279 WP_002804296.1 CopG family ribbon-helix-helix protein Antitoxin
BER93_RS23035 2924..3472 + 549 WP_002804297.1 hypothetical protein -
BER93_RS19585 3462..4109 + 648 WP_002804298.1 recombinase family protein -
BER93_RS23040 4106..4243 + 138 WP_167699514.1 hypothetical protein -
BER93_RS19590 4353..4985 + 633 WP_002804299.1 ParA family protein -
BER93_RS19595 4978..5340 + 363 WP_002804300.1 hypothetical protein -
BER93_RS19600 5423..5746 + 324 WP_002804301.1 hypothetical protein -
BER93_RS19605 5940..7349 + 1410 WP_002804302.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..20831 20831


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10801.49 Da        Isoelectric Point: 10.0858

>T65190 WP_002804295.1 NZ_CP016835:c2374-2090 [Xanthomonas fragariae]
VPHLIWTPPALADVQRLYRFLAPKDADAARRAVQAIRAQVKILAHQPRIGRPVEDMAPEFRDWLIDFGDSGYVARYRINE
NMVTILAVRHQKEA

Download         Length: 285 bp

>T65190 NZ_CP016835:c2374-2090 [Xanthomonas fragariae]
GTGCCACACCTGATTTGGACGCCGCCGGCACTCGCGGACGTTCAACGCCTGTATCGTTTCCTTGCTCCGAAGGATGCCGA
CGCTGCCCGCCGTGCGGTGCAAGCAATCCGCGCGCAGGTCAAAATCCTGGCGCATCAGCCTCGCATCGGGCGACCCGTCG
AGGACATGGCCCCCGAGTTCCGCGATTGGCTCATCGACTTTGGCGATAGCGGCTACGTGGCCCGGTATCGCATCAACGAA
AACATGGTGACGATCTTGGCCGTTCGGCACCAAAAGGAAGCGTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10760.05 Da        Isoelectric Point: 5.1991

>AT65190 WP_002804296.1 NZ_CP016835:c2640-2362 [Xanthomonas fragariae]
MASPTSLKLDDELKGRVQHLAQTQRRTPHWIMREAIAQYVEREEKRETFKQDALRAWEDYQRTGLHLTLEETDAWLAKLE
AGEDAELPACHT

Download         Length: 279 bp

>AT65190 NZ_CP016835:c2640-2362 [Xanthomonas fragariae]
ATGGCATCGCCAACCTCGCTCAAGCTCGATGACGAGCTGAAAGGGCGTGTGCAACACCTCGCCCAAACCCAGCGCCGCAC
GCCGCACTGGATCATGCGTGAAGCCATTGCGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGACCTTCAAACAAGACGCGC
TCCGCGCTTGGGAGGACTATCAGCGCACCGGCCTGCACCTGACGCTCGAAGAAACCGATGCGTGGCTGGCCAAGCTCGAA
GCTGGCGAGGATGCGGAACTGCCAGCGTGCCACACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HCU7

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6HDJ6

References