Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 23738..24317 Replicon plasmid pFap29-1
Accession NZ_CP016834
Organism Xanthomonas fragariae isolate Fap29

Toxin (Protein)


Gene name relE Uniprot ID A0A1Y6HD38
Locus tag BER93_RS19525 Protein ID WP_002805372.1
Coordinates 24024..24317 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1Y6HUN4
Locus tag BER93_RS19520 Protein ID WP_002805369.1
Coordinates 23738..24037 (+) Length 100 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BER93_RS19495 19326..21170 + 1845 WP_065975501.1 hypothetical protein -
BER93_RS19500 21167..21790 + 624 WP_002805358.1 transglycosylase SLT domain-containing protein -
BER93_RS19505 21787..22056 + 270 WP_052032117.1 DUF3717 domain-containing protein -
BER93_RS19510 22217..22792 - 576 WP_065975506.1 recombinase family protein -
BER93_RS21620 22834..23259 - 426 WP_167699513.1 antitoxin VbhA family protein -
BER93_RS19520 23738..24037 + 300 WP_002805369.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BER93_RS19525 24024..24317 + 294 WP_002805372.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BER93_RS22660 24395..24571 + 177 WP_156775376.1 hypothetical protein -
BER93_RS19530 24568..24792 - 225 WP_002805375.1 hypothetical protein -
BER93_RS19535 25013..25765 + 753 WP_065975503.1 hypothetical protein -
BER93_RS19545 26269..26868 - 600 WP_065975504.1 hypothetical protein -
BER93_RS19550 27526..28545 - 1020 WP_052032118.1 relaxase/mobilization nuclease domain-containing protein -
BER93_RS19555 28532..29083 - 552 WP_065975505.1 plasmid mobilization relaxosome protein MobC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..29138 29138


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-55)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10915.49 Da        Isoelectric Point: 5.1409

>T65189 WP_002805372.1 NZ_CP016834:24024-24317 [Xanthomonas fragariae]
VLVLEWRETARADLLAIVDYISDDNPDAAQRLKDDIEAKASMLPERPKLYRPGRVAGTREMVVRSNYVVVYAEDARAVSI
LRVLHAAQQWPPVTGVE

Download         Length: 294 bp

>T65189 NZ_CP016834:24024-24317 [Xanthomonas fragariae]
GTGCTCGTTCTTGAGTGGCGCGAGACAGCCCGCGCCGATCTGCTGGCGATTGTCGATTACATATCCGACGACAACCCGGA
TGCAGCGCAGCGGTTGAAAGATGACATCGAGGCCAAGGCCTCGATGCTGCCTGAGCGCCCGAAGCTGTATCGGCCTGGTC
GCGTCGCCGGCACTCGGGAAATGGTCGTCCGATCGAACTACGTGGTGGTGTACGCGGAAGACGCGCGCGCCGTTTCCATC
CTGCGGGTGCTGCATGCGGCCCAACAGTGGCCGCCAGTGACCGGGGTTGAGTGA

Antitoxin


Download         Length: 100 a.a.        Molecular weight: 10717.25 Da        Isoelectric Point: 8.9086

>AT65189 WP_002805369.1 NZ_CP016834:23738-24037 [Xanthomonas fragariae]
MAAHTSMLHIRVDDALKAQAAETLANVGLTVSDAVRILLTRVAKEGGLPAGLTADPEAHDAWFRGKVQEALADTRPAVPH
RQVMDEAQALIDRKRRARS

Download         Length: 300 bp

>AT65189 NZ_CP016834:23738-24037 [Xanthomonas fragariae]
ATGGCTGCTCACACCTCGATGCTGCATATCCGCGTCGATGACGCTCTAAAGGCACAGGCTGCCGAGACGCTCGCCAATGT
CGGCCTGACGGTCTCGGATGCTGTGCGCATCCTGCTGACCCGCGTCGCCAAGGAAGGCGGGTTGCCAGCCGGCCTGACGG
CCGATCCAGAGGCCCACGACGCCTGGTTCCGGGGCAAGGTGCAAGAGGCCCTGGCCGACACGCGGCCGGCGGTGCCGCAT
CGCCAGGTGATGGATGAGGCGCAAGCCCTGATCGACCGGAAACGCCGTGCTCGTTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HD38

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6HUN4

References