65182

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 302038..302404 Replicon chromosome
Accession NZ_CP016830
Organism Xanthomonas fragariae isolate Fap21

Toxin (Protein)


Gene name EcnB Uniprot ID A0A1Y6HEL5
Locus tag BER92_RS01340 Protein ID WP_002809516.1
Coordinates 302038..302172 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A1Y6GQE1
Locus tag BER92_RS01345 Protein ID WP_002809518.1
Coordinates 302252..302404 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BER92_RS01320 297171..298286 + 1116 WP_002809491.1 alpha/beta fold hydrolase -
BER92_RS01325 298346..299255 - 910 Protein_263 EamA family transporter RarD -
BER92_RS19790 299271..299876 - 606 Protein_264 drug/metabolite exporter YedA -
BER92_RS01330 300037..300237 - 201 Protein_265 peptidase M20 -
BER92_RS01335 300420..301709 - 1290 WP_002809514.1 tryptophan--tRNA ligase -
BER92_RS01340 302038..302172 - 135 WP_002809516.1 entericidin A/B family lipoprotein Toxin
BER92_RS01345 302252..302404 - 153 WP_002809518.1 entericidin A/B family lipoprotein Antitoxin
BER92_RS01350 302513..303436 - 924 WP_002809521.1 arginase -
BER92_RS01355 303794..304187 + 394 Protein_270 roadblock/LC7 domain-containing protein -
BER92_RS19795 304210..304440 + 231 Protein_271 GTPase -
BER92_RS19800 305982..305983 - 2 WP_088056924.1 IS5 family transposase -
BER92_RS19805 306720..307066 + 347 Protein_273 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4425.27 Da        Isoelectric Point: 10.2040

>T65182 WP_002809516.1 NZ_CP016830:c302172-302038 [Xanthomonas fragariae]
MKRAIVLLVLSVLSVGILSGCNTVAGAGKDVKGAGEKVEDAARK

Download         Length: 135 bp

>T65182 NZ_CP016830:c302172-302038 [Xanthomonas fragariae]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGGTGTTGTCGGTCGGTATACTGTCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGAAGGGCGCTGGCGAGAAGGTGGAAGACGCTGCGCGCAAGTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5241.20 Da        Isoelectric Point: 9.4952

>AT65182 WP_002809518.1 NZ_CP016830:c302404-302252 [Xanthomonas fragariae]
MKRLLTLMVLGLFSAGVMTGCNTFAGAGKDMQRAGSKVEKKADNCSDGKC

Download         Length: 153 bp

>AT65182 NZ_CP016830:c302404-302252 [Xanthomonas fragariae]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACTGGCTGTAACACCTTTGCTGGCGC
CGGCAAGGATATGCAACGCGCGGGCAGCAAGGTCGAAAAGAAGGCCGATAACTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1Y6HEL5

Antitoxin

Source ID Structure
AlphaFold DB A0A1Y6GQE1

References