Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 2028666..2029231 Replicon chromosome
Accession NZ_CP016819
Organism Rhodococcus sp. p52

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag IM25_RS09455 Protein ID WP_198162551.1
Coordinates 2028953..2029231 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag IM25_RS09450 Protein ID WP_006551856.1
Coordinates 2028666..2028956 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
IM25_RS09425 2023899..2024501 + 603 WP_065995988.1 TetR/AcrR family transcriptional regulator -
IM25_RS09430 2024498..2024926 + 429 WP_024102975.1 HIT family protein -
IM25_RS09435 2024931..2026532 + 1602 WP_033096850.1 L-lactate permease -
IM25_RS09440 2026609..2027637 + 1029 WP_065995989.1 Dyp-type peroxidase -
IM25_RS09445 2027634..2028452 + 819 WP_006551857.1 bacteriocin family protein -
IM25_RS09450 2028666..2028956 + 291 WP_006551856.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
IM25_RS09455 2028953..2029231 + 279 WP_198162551.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
IM25_RS09460 2029288..2029767 - 480 WP_065995990.1 MarR family transcriptional regulator -
IM25_RS09465 2029826..2030575 - 750 WP_024102983.1 cutinase family protein -
IM25_RS09470 2030725..2031387 - 663 WP_033096847.1 alpha-ketoglutarate-dependent dioxygenase AlkB -
IM25_RS09475 2031508..2032338 + 831 WP_006551851.1 SDR family oxidoreductase -
IM25_RS09480 2032383..2033354 + 972 WP_006551850.1 phosphotriesterase -
IM25_RS09485 2033391..2034110 - 720 WP_033096970.1 2OG-Fe(II) oxygenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(40-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-73)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10226.74 Da        Isoelectric Point: 10.2002

>T65156 WP_198162551.1 NZ_CP016819:2028953-2029231 [Rhodococcus sp. p52]
MSTPDHPYRLGMARSAARAMARSLPEKVATAVYEFVTGPLLENPKRVGKPLNPPLAPAYSARRGEYRVLYLIDDANRTVE
VTAISHRADAYR

Download         Length: 279 bp

>T65156 NZ_CP016819:2028953-2029231 [Rhodococcus sp. p52]
ATGAGCACTCCGGACCACCCGTATCGGCTGGGGATGGCGAGGTCGGCTGCACGCGCCATGGCGAGGTCGTTGCCGGAGAA
GGTAGCAACTGCGGTATACGAGTTCGTCACAGGACCCCTTCTCGAGAATCCGAAGCGGGTGGGGAAGCCGTTGAATCCGC
CTCTTGCGCCGGCGTACAGCGCCCGGCGAGGTGAATATCGCGTCCTGTATCTGATCGATGATGCGAACCGCACGGTCGAG
GTCACCGCGATTTCGCACCGTGCCGATGCGTATCGATAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10788.92 Da        Isoelectric Point: 4.2336

>AT65156 WP_006551856.1 NZ_CP016819:2028666-2028956 [Rhodococcus sp. p52]
MYMTTLPVADARAQLSRLVDEAERTHERFEITRNGHRAAVLLGADDYDAMQETIAVLSDTDLLRAHVEGRTEVESGDVVD
VQELTQLMRDARSSEE

Download         Length: 291 bp

>AT65156 NZ_CP016819:2028666-2028956 [Rhodococcus sp. p52]
ATGTACATGACGACTCTTCCTGTTGCCGACGCGCGGGCGCAATTGTCACGACTGGTCGATGAGGCCGAGCGCACACACGA
GCGATTCGAGATCACCCGCAACGGGCACCGCGCCGCGGTGCTTCTCGGTGCCGACGATTACGACGCGATGCAGGAGACGA
TCGCGGTGTTGTCGGATACGGATCTGCTGCGGGCGCACGTCGAGGGCCGAACGGAGGTCGAGTCGGGAGACGTCGTCGAT
GTACAGGAATTGACGCAGCTGATGCGTGATGCTCGGTCGTCCGAGGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References