Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3350094..3350239 Replicon chromosome
Accession NZ_CP016814
Organism Klebsiella pneumoniae strain ED23

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3350101..3350203 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3350094..3350239 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCV49_RS16420 3345626..3347059 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BCV49_RS16425 3347175..3347414 + 240 WP_002911393.1 YebV family protein -
BCV49_RS16430 3347512..3347703 + 192 WP_002911395.1 YebW family protein -
BCV49_RS16435 3347700..3348353 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
BCV49_RS16440 3348510..3349478 + 969 WP_014907334.1 VirK/YbjX family protein -
BCV49_RS29620 3349583..3349726 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3350094..3350239 + 146 - - Antitoxin
- 3350101..3350203 - 103 - - Toxin
BCV49_RS16450 3350362..3350700 - 339 WP_002911404.1 YebY family protein -
BCV49_RS16455 3350717..3351586 - 870 WP_014907333.1 copper homeostasis membrane protein CopD -
BCV49_RS16460 3351590..3351964 - 375 WP_068987078.1 CopC domain-containing protein YobA -
BCV49_RS16465 3352077..3352307 + 231 WP_002911406.1 DNA polymerase III subunit theta -
BCV49_RS16470 3352386..3353045 + 660 WP_002911407.1 exodeoxyribonuclease X -
BCV49_RS16475 3353049..3355109 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T65138 NZ_CP016814:c3350203-3350101 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT65138 NZ_CP016814:3350094-3350239 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References