Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2405328..2405473 Replicon chromosome
Accession NZ_CP016813
Organism Klebsiella pneumoniae strain ED2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2405364..2405466 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2405328..2405473 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCV48_RS11385 2400458..2402518 + 2061 WP_004151449.1 oligopeptidase B -
BCV48_RS11390 2402522..2403181 - 660 WP_002911407.1 exodeoxyribonuclease X -
BCV48_RS11395 2403260..2403490 - 231 WP_002911406.1 DNA polymerase III subunit theta -
BCV48_RS11400 2403603..2403977 + 375 WP_004151448.1 CopC domain-containing protein YobA -
BCV48_RS11405 2403981..2404850 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
BCV48_RS11410 2404867..2405205 + 339 WP_002911404.1 YebY family protein -
- 2405328..2405473 - 146 - - Antitoxin
- 2405364..2405466 + 103 - - Toxin
BCV48_RS28655 2405841..2405984 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
BCV48_RS11420 2406089..2407057 - 969 WP_014907334.1 VirK/YbjX family protein -
BCV48_RS11425 2407214..2407867 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
BCV48_RS11430 2407864..2408055 - 192 WP_002911395.1 YebW family protein -
BCV48_RS11435 2408153..2408392 - 240 WP_002911393.1 YebV family protein -
BCV48_RS11440 2408508..2409941 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T65121 NZ_CP016813:2405364-2405466 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT65121 NZ_CP016813:c2405473-2405328 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References