Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 917615..917760 Replicon chromosome
Accession NZ_CP016811
Organism Klebsiella pneumoniae strain DHQP1002001

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 917651..917753 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 917615..917760 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
A8C02_RS05985 912745..914805 + 2061 WP_004151449.1 oligopeptidase B -
A8C02_RS05990 914809..915468 - 660 WP_002911407.1 exodeoxyribonuclease X -
A8C02_RS05995 915547..915777 - 231 WP_002911406.1 DNA polymerase III subunit theta -
A8C02_RS06000 915890..916264 + 375 WP_004151448.1 CopC domain-containing protein YobA -
A8C02_RS06005 916268..917137 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
A8C02_RS06010 917154..917492 + 339 WP_016529031.1 YebY family protein -
- 917615..917760 - 146 - - Antitoxin
- 917651..917753 + 103 - - Toxin
A8C02_RS30800 918129..918272 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
A8C02_RS06020 918377..919345 - 969 WP_004151446.1 VirK/YbjX family protein -
A8C02_RS06025 919502..920155 + 654 WP_019725444.1 protein-serine/threonine phosphatase -
A8C02_RS06030 920152..920343 - 192 WP_002911395.1 YebW family protein -
A8C02_RS06035 920441..920680 - 240 WP_002911393.1 YebV family protein -
A8C02_RS06040 920796..922229 - 1434 WP_032415191.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T65099 NZ_CP016811:917651-917753 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT65099 NZ_CP016811:c917760-917615 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References