65021

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 2647619..2647964 Replicon chromosome
Accession NZ_CP016756
Organism Stenotrophomonas nitritireducens strain 2001

Toxin (Protein)


Gene name EcnB Uniprot ID A0A126NMD1
Locus tag BCV67_RS11075 Protein ID WP_062170399.1
Coordinates 2647827..2647964 (+) Length 46 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A126NT85
Locus tag BCV67_RS11070 Protein ID WP_062171871.1
Coordinates 2647619..2647771 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCV67_RS11055 2643627..2644058 - 432 WP_062170404.1 CBS domain-containing protein -
BCV67_RS11060 2644717..2646360 + 1644 WP_065868108.1 mechanosensitive ion channel family protein -
BCV67_RS11065 2646559..2647479 + 921 WP_062170401.1 arginase -
BCV67_RS11070 2647619..2647771 + 153 WP_062171871.1 entericidin A/B family lipoprotein Antitoxin
BCV67_RS11075 2647827..2647964 + 138 WP_062170399.1 entericidin A/B family lipoprotein Toxin
BCV67_RS11080 2648163..2648384 + 222 WP_062170397.1 CsbD family protein -
BCV67_RS11085 2648702..2649529 - 828 WP_062170395.1 hypothetical protein -
BCV67_RS11090 2649651..2650952 + 1302 WP_062170393.1 tryptophan--tRNA ligase -
BCV67_RS11095 2650975..2651268 + 294 WP_062170391.1 hypothetical protein -
BCV67_RS11100 2651354..2652286 + 933 WP_062170389.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 46 a.a.        Molecular weight: 4556.42 Da        Isoelectric Point: 10.2067

>T65021 WP_062170399.1 NZ_CP016756:2647827-2647964 [Stenotrophomonas nitritireducens]
MKRLVALMLLSLFSVAVLSGCNTVAGAGKDVQKAGEKVEGAAKGH

Download         Length: 138 bp

>T65021 NZ_CP016756:2647827-2647964 [Stenotrophomonas nitritireducens]
ATGAAGCGTTTGGTCGCCCTGATGTTGTTGTCGCTGTTTTCGGTTGCGGTGCTGTCTGGCTGCAATACCGTGGCCGGTGC
CGGCAAGGATGTGCAGAAGGCTGGTGAGAAGGTTGAGGGTGCTGCCAAGGGTCATTGA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5209.17 Da        Isoelectric Point: 8.2766

>AT65021 WP_062171871.1 NZ_CP016756:2647619-2647771 [Stenotrophomonas nitritireducens]
MKRVMMLALVGAFSVGMLSGCNTVAGAGKDMQKAGEKVEDKAQDCKDGKC

Download         Length: 153 bp

>AT65021 NZ_CP016756:2647619-2647771 [Stenotrophomonas nitritireducens]
ATGAAGCGAGTGATGATGTTGGCCCTGGTGGGCGCGTTCTCGGTTGGCATGCTCAGCGGCTGCAATACCGTCGCCGGCGC
CGGCAAGGACATGCAGAAGGCCGGTGAGAAGGTCGAAGACAAGGCCCAGGATTGTAAAGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A126NMD1

Antitoxin

Source ID Structure
AlphaFold DB A0A126NT85

References