Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 2460654..2461216 Replicon chromosome
Accession NZ_CP016616
Organism Microvirga ossetica strain V5/3m

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BB934_RS11520 Protein ID WP_099509757.1
Coordinates 2460848..2461216 (+) Length 123 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BB934_RS11515 Protein ID WP_099509756.1
Coordinates 2460654..2460851 (+) Length 66 a.a.

Genomic Context

BB934_RS11510BB934_RS11515BB934_RS11520BB934_RS11525BB934_RS11530BB934_RS11500BB934_RS11505
Location: 2459104..2460336 (1233 bp)
Type: Others
Protein ID: WP_099509755.1
Location: 2460654..2460851 (198 bp)
Type: Antitoxin
Protein ID: WP_099509756.1
Location: 2460848..2461216 (369 bp)
Type: Toxin
Protein ID: WP_099509757.1
Location: 2461399..2462256 (858 bp)
Type: Others
Protein ID: WP_099509758.1
Location: 2463620..2465446 (1827 bp)
Type: Others
Protein ID: WP_099509759.1
Location: 2456241..2457938 (1698 bp)
Type: Others
Protein ID: WP_099509754.1
Location: 2458237..2458865 (629 bp)
Type: Others
Protein ID: Protein_2230
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BB934_RS115002456241..2457938-1698WP_099509754.130S ribosomal protein S1-
BB934_RS115052458237..2458865-629Protein_22302-hydroxychromene-2-carboxylate isomerase-
BB934_RS115102459104..2460336+1233WP_099509755.1argininosuccinate synthase-
BB934_RS115152460654..2460851+198WP_099509756.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
BB934_RS115202460848..2461216+369WP_099509757.1type II toxin-antitoxin system VapC family toxinToxin
BB934_RS115252461399..2462256+858WP_099509758.1GNAT family N-acetyltransferase-
BB934_RS115302463620..2465446+1827WP_099509759.1translational GTPase TypA-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-112)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-44)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13370.44 Da        Isoelectric Point: 5.5461

>T64863 WP_099509757.1 NZ_CP016616:2460848-2461216 [Microvirga ossetica]
MILVDTSVWIDHLKTGDDNLARLLEAGRVLMHPFVLGELALGSLRNRQTILELLGQLPRAEMATDQEVLSLIEAETLHGT
GIGLIDAHLLASAKLTAGSSLWTRDKRLERLAARLHGSTELE

Download         Length: 369 bp

>T64863 NZ_CP016616:2460848-2461216 [Microvirga ossetica]
ATGATCCTGGTCGACACCTCCGTCTGGATCGATCATCTCAAAACGGGCGACGACAACTTGGCCCGCCTCCTGGAAGCCGG
CCGCGTCCTCATGCATCCTTTCGTGCTGGGCGAGCTTGCACTCGGCAGCCTCCGGAACCGACAAACCATTCTTGAACTGC
TCGGACAATTGCCTCGGGCGGAAATGGCAACGGACCAGGAAGTCTTGAGTCTCATCGAAGCGGAAACCCTCCATGGCACC
GGCATCGGCCTCATCGATGCCCATCTTCTCGCTTCGGCGAAGCTGACGGCGGGATCATCCCTGTGGACCCGCGATAAAAG
GCTCGAGCGTCTGGCCGCACGACTGCACGGGTCCACGGAGCTTGAATAA

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7136.27 Da        Isoelectric Point: 10.9487

>AT64863 WP_099509756.1 NZ_CP016616:2460654-2460851 [Microvirga ossetica]
MRTTIALDDSLVAKAQAMTGLREKSALVREALEALIQRESARRLAKLGGSEPDLRPIPRRQPDPA

Download         Length: 198 bp

>AT64863 NZ_CP016616:2460654-2460851 [Microvirga ossetica]
ATGCGCACGACCATTGCCCTGGATGACAGTCTTGTTGCGAAGGCGCAGGCGATGACGGGTCTGCGCGAGAAATCCGCCCT
GGTTCGAGAGGCTTTGGAAGCCTTGATTCAGCGTGAAAGCGCGCGGCGCCTCGCCAAGCTCGGCGGCAGCGAGCCGGATC
TGCGACCCATCCCGCGGCGGCAGCCCGATCCCGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References