64862

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1105139..1105770 Replicon chromosome
Accession NZ_CP016616
Organism Microvirga ossetica strain V5/3m

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BB934_RS05180 Protein ID WP_099508675.1
Coordinates 1105139..1105552 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag BB934_RS05185 Protein ID WP_099512639.1
Coordinates 1105552..1105770 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BB934_RS05155 1100430..1101761 - 1332 WP_099508671.1 NCS2 family nucleobase:cation symporter -
BB934_RS05160 1101925..1102944 + 1020 WP_099512638.1 enterochelin esterase -
BB934_RS05165 1102952..1103899 - 948 WP_099508672.1 NAD(P)/FAD-dependent oxidoreductase -
BB934_RS05170 1104118..1104672 + 555 WP_099508673.1 hypothetical protein -
BB934_RS05175 1104685..1105062 + 378 WP_099508674.1 HNH endonuclease -
BB934_RS05180 1105139..1105552 - 414 WP_099508675.1 type II toxin-antitoxin system VapC family toxin Toxin
BB934_RS05185 1105552..1105770 - 219 WP_099512639.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BB934_RS05190 1105863..1106165 - 303 WP_099508676.1 hypothetical protein -
BB934_RS05200 1106532..1107335 - 804 WP_157934043.1 hypothetical protein -
BB934_RS46895 1109096..1109470 + 375 WP_157934044.1 HNH endonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(6-127)

Antitoxin

SpoVT-AbrB domain

(7-40)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15135.61 Da        Isoelectric Point: 8.0125

>T64862 WP_099508675.1 NZ_CP016616:c1105552-1105139 [Microvirga ossetica]
MAQPHYLLDTNICIYIRRERPQAVLNRFKVLPPGSTAISVITYGELVYGVRKSSDPDKAMMVLEELTELIPVVPMAIDVA
EAYGRIRSDLAARGALIGNNDLWIAAHAVSLKLTLVTNNEKAFQRVSGLTLENWAKG

Download         Length: 414 bp

>T64862 NZ_CP016616:c1105552-1105139 [Microvirga ossetica]
ATGGCCCAGCCCCATTATCTCCTCGACACCAACATCTGCATCTACATTCGCCGGGAGCGTCCACAAGCCGTCCTCAATCG
GTTCAAAGTCCTGCCCCCAGGCTCGACAGCCATTTCCGTCATTACCTACGGCGAGCTGGTCTACGGGGTCCGGAAAAGCT
CCGACCCCGATAAGGCGATGATGGTTCTGGAGGAGCTGACAGAGCTAATCCCCGTCGTCCCGATGGCCATCGATGTGGCC
GAAGCCTATGGACGCATCCGGTCAGACCTCGCCGCTCGCGGCGCCTTGATCGGCAACAACGATCTCTGGATCGCAGCTCA
TGCCGTGAGCCTCAAACTCACGCTGGTGACCAACAACGAGAAAGCGTTCCAGAGGGTCAGCGGCCTCACTCTCGAGAACT
GGGCCAAGGGATAG

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8309.56 Da        Isoelectric Point: 9.3405

>AT64862 WP_099512639.1 NZ_CP016616:c1105770-1105552 [Microvirga ossetica]
MAIAKVFRSGNSQAVRLPKQFRLTRDEVEIFRRGDEIVLREKPKTLARAFELLCNLPDWTQEDAPPQGREGL

Download         Length: 219 bp

>AT64862 NZ_CP016616:c1105770-1105552 [Microvirga ossetica]
ATGGCCATCGCCAAGGTGTTTCGGTCCGGCAACAGTCAGGCCGTCCGGCTGCCCAAGCAGTTTCGCCTTACCCGTGATGA
GGTCGAGATTTTCCGCCGCGGCGATGAAATCGTGCTGCGGGAAAAACCCAAGACGCTGGCGCGGGCGTTCGAGCTGCTGT
GTAACCTCCCTGATTGGACCCAGGAGGATGCCCCGCCACAGGGGCGCGAGGGGCTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References