Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 578780..579309 Replicon plasmid unnamed1
Accession NZ_CP016613
Organism Ralstonia solanacearum FJAT-91

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BC427_RS20555 Protein ID WP_016722340.1
Coordinates 578780..579007 (+) Length 76 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BC427_RS20560 Protein ID WP_016722339.1
Coordinates 579004..579309 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BC427_RS20535 575017..575616 - 600 WP_016722344.1 GNAT family N-acetyltransferase -
BC427_RS20540 575749..576300 + 552 WP_016722343.1 helix-turn-helix transcriptional regulator -
BC427_RS20545 576478..577299 + 822 WP_011003398.1 GntR family transcriptional regulator -
BC427_RS20550 577426..578625 + 1200 WP_016726513.1 MFS transporter -
BC427_RS20555 578780..579007 + 228 WP_016722340.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BC427_RS20560 579004..579309 + 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
BC427_RS20565 579522..580835 + 1314 WP_038938025.1 metabolite/H+ symporter -
BC427_RS20570 580940..581608 - 669 WP_038938024.1 hypothetical protein -
BC427_RS26580 581775..581992 - 218 Protein_460 transposase -
BC427_RS20575 582297..582581 + 285 WP_011003391.1 hypothetical protein -
BC427_RS20580 582712..582993 + 282 WP_016722336.1 hypothetical protein -
BC427_RS20585 583324..583809 - 486 WP_016726511.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - fliI / fliG / fliM / flgG / flgC / cyaB / motA / cheW / cheB / cheY / adeG / htpB / acrB 1..2000873 2000873
- flank IS/Tn - - 584044..585009 965


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-67)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 76 a.a.        Molecular weight: 8566.85 Da        Isoelectric Point: 7.2789

>T64861 WP_016722340.1 NZ_CP016613:578780-579007 [Ralstonia solanacearum FJAT-91]
VRIDRLQMGHPGNMKAVRDGIRELRIDHGPGDRLYFVRHGVVLIVLLCGGDKSTQETDIRRAIDLSRRLDVDDME

Download         Length: 228 bp

>T64861 NZ_CP016613:578780-579007 [Ralstonia solanacearum FJAT-91]
GTGCGCATCGACCGCCTGCAGATGGGCCACCCAGGCAACATGAAAGCGGTCCGTGACGGCATCCGTGAGCTGCGGATCGA
TCATGGGCCGGGCGACCGCTTGTACTTCGTGCGGCATGGCGTGGTCCTGATCGTACTGCTCTGCGGCGGCGACAAGTCGA
CGCAGGAAACCGATATCCGTCGCGCAATTGACCTGTCCCGCCGTCTCGACGTGGACGACATGGAATGA

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT64861 WP_016722339.1 NZ_CP016613:579004-579309 [Ralstonia solanacearum FJAT-91]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp

>AT64861 NZ_CP016613:579004-579309 [Ralstonia solanacearum FJAT-91]
ATGACGATGGCCCAACGCACCATCAAGACCCGGCCGTGGGATTCGGCCGAACACCTCCGGACCGAAGCGGACATCGCCGC
CTACCTCGACGCCTGCCTGGAAGAAGCCGGAGATGACCCCGCCTTCATCACGCATGCGCTGGGCGTGGTCGCGCGCTCGC
GCGGCATGACGCAGCTCGCCCGCGAGACCGGGATGACCCGCGAGGGGCTGTACAAGGCGCTTTCCGAGGGCGGCAATCCG
AGCTTTGCGACCGTGCTGAAGGTCATCCGGGCGCTCGGCATCCGGCTGCACGCCGTGCCGACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References