Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
| Location | 1390394..1390986 | Replicon | chromosome |
| Accession | NZ_CP016610 | ||
| Organism | Xylella fastidiosa strain Salento-2 | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | A0A060HCK8 |
| Locus tag | BC375_RS06935 | Protein ID | WP_004085590.1 |
| Coordinates | 1390394..1390690 (+) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | PumB | Uniprot ID | - |
| Locus tag | BC375_RS06940 | Protein ID | WP_004085592.1 |
| Coordinates | 1390693..1390986 (+) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BC375_RS06900 (BC375_06440) | 1385986..1386360 | + | 375 | WP_060870180.1 | hypothetical protein | - |
| BC375_RS06905 (BC375_06445) | 1386441..1386656 | + | 216 | WP_230949859.1 | helix-turn-helix domain-containing protein | - |
| BC375_RS06910 (BC375_06450) | 1386703..1387194 | + | 492 | WP_230951054.1 | DUF4065 domain-containing protein | - |
| BC375_RS06915 (BC375_06455) | 1387197..1387421 | + | 225 | WP_230949856.1 | hypothetical protein | - |
| BC375_RS06920 (BC375_06460) | 1387422..1388585 | - | 1164 | WP_046419971.1 | tail fiber protein | - |
| BC375_RS06925 (BC375_06465) | 1388589..1389149 | - | 561 | WP_046419969.1 | DUF2612 domain-containing protein | - |
| BC375_RS06930 (BC375_06470) | 1389146..1390291 | - | 1146 | WP_046419967.1 | baseplate J/gp47 family protein | - |
| BC375_RS06935 (BC375_06475) | 1390394..1390690 | + | 297 | WP_004085590.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| BC375_RS06940 (BC375_06480) | 1390693..1390986 | + | 294 | WP_004085592.1 | putative addiction module antidote protein | Antitoxin |
| BC375_RS06945 (BC375_06485) | 1391042..1391395 | - | 354 | WP_046419963.1 | hypothetical protein | - |
| BC375_RS06950 (BC375_06490) | 1391392..1392033 | - | 642 | WP_046419962.1 | Gp138 family membrane-puncturing spike protein | - |
| BC375_RS06955 (BC375_06495) | 1392030..1392860 | - | 831 | WP_046419672.1 | hypothetical protein | - |
| BC375_RS06960 (BC375_06500) | 1392857..1393174 | - | 318 | WP_046419669.1 | hypothetical protein | - |
| BC375_RS06965 (BC375_06505) | 1393174..1393944 | - | 771 | WP_046419667.1 | hypothetical protein | - |
| BC375_RS06970 (BC375_06510) | 1394352..1394609 | - | 258 | WP_046419904.1 | Blp family class II bacteriocin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 1359018..1459171 | 100153 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11169.70 Da Isoelectric Point: 10.0610
>T64855 WP_004085590.1 NZ_CP016610:1390394-1390690 [Xylella fastidiosa]
MIELKQTDTFRKWREKLKDARARSAIASRLDRLAFGHVGDAEPVGKGVSELRINYGPGYRVYFQRRGDTIYLLLCGGDKG
SQARDIKTALHLSEQWSE
MIELKQTDTFRKWREKLKDARARSAIASRLDRLAFGHVGDAEPVGKGVSELRINYGPGYRVYFQRRGDTIYLLLCGGDKG
SQARDIKTALHLSEQWSE
Download Length: 297 bp
>T64855 NZ_CP016610:1390394-1390690 [Xylella fastidiosa]
ATGATTGAATTGAAGCAGACTGACACCTTCCGCAAGTGGCGGGAGAAACTCAAGGATGCGCGCGCCCGCTCGGCCATCGC
CTCGCGCCTCGACCGCTTGGCGTTCGGCCATGTCGGCGACGCGGAGCCAGTAGGGAAAGGTGTCAGCGAGCTTCGCATCA
ACTACGGCCCCGGTTACCGGGTGTATTTCCAGCGGCGTGGCGACACGATCTACTTGCTGCTTTGCGGCGGTGACAAAGGA
TCACAAGCGCGCGACATCAAGACTGCGCTGCACCTGTCTGAACAATGGAGCGAATGA
ATGATTGAATTGAAGCAGACTGACACCTTCCGCAAGTGGCGGGAGAAACTCAAGGATGCGCGCGCCCGCTCGGCCATCGC
CTCGCGCCTCGACCGCTTGGCGTTCGGCCATGTCGGCGACGCGGAGCCAGTAGGGAAAGGTGTCAGCGAGCTTCGCATCA
ACTACGGCCCCGGTTACCGGGTGTATTTCCAGCGGCGTGGCGACACGATCTACTTGCTGCTTTGCGGCGGTGACAAAGGA
TCACAAGCGCGCGACATCAAGACTGCGCTGCACCTGTCTGAACAATGGAGCGAATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10246.59 Da Isoelectric Point: 5.6232
>AT64855 WP_004085592.1 NZ_CP016610:1390693-1390986 [Xylella fastidiosa]
MTEKLTSYDPAEDLTTDQAIADFMAAAFGTNDPAYVAHALGVVARAKGMTQIASQTGLSREQLYRSFSAEGNPTLRTTLA
VMKALGIELSAKPSGVH
MTEKLTSYDPAEDLTTDQAIADFMAAAFGTNDPAYVAHALGVVARAKGMTQIASQTGLSREQLYRSFSAEGNPTLRTTLA
VMKALGIELSAKPSGVH
Download Length: 294 bp
>AT64855 NZ_CP016610:1390693-1390986 [Xylella fastidiosa]
ATGACCGAGAAACTGACGAGCTACGATCCAGCCGAGGACTTGACCACTGACCAGGCCATCGCCGATTTCATGGCAGCTGC
GTTCGGGACGAACGATCCTGCCTACGTTGCCCACGCGCTGGGCGTCGTTGCCCGCGCCAAGGGCATGACGCAGATCGCCA
GCCAAACAGGGCTATCGCGCGAACAGCTCTACCGCTCGTTCAGTGCCGAGGGCAACCCAACGCTGCGCACGACATTGGCC
GTGATGAAGGCGCTAGGGATCGAGCTGTCTGCGAAACCGTCGGGTGTTCACTGA
ATGACCGAGAAACTGACGAGCTACGATCCAGCCGAGGACTTGACCACTGACCAGGCCATCGCCGATTTCATGGCAGCTGC
GTTCGGGACGAACGATCCTGCCTACGTTGCCCACGCGCTGGGCGTCGTTGCCCGCGCCAAGGGCATGACGCAGATCGCCA
GCCAAACAGGGCTATCGCGCGAACAGCTCTACCGCTCGTTCAGTGCCGAGGGCAACCCAACGCTGCGCACGACATTGGCC
GTGATGAAGGCGCTAGGGATCGAGCTGTCTGCGAAACCGTCGGGTGTTCACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|