64854

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1383067..1383659 Replicon chromosome
Accession NZ_CP016610
Organism Xylella fastidiosa strain Salento-2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BC375_RS06875 Protein ID WP_046419679.1
Coordinates 1383067..1383363 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag BC375_RS06880 Protein ID WP_004085592.1
Coordinates 1383366..1383659 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BC375_RS06845 (BC375_06385) 1378605..1379183 - 579 WP_046419686.1 glutathione peroxidase -
BC375_RS12350 1379549..1379710 - 162 WP_010894100.1 hypothetical protein -
BC375_RS06855 (BC375_06395) 1379929..1380804 + 876 WP_023906641.1 ABC transporter ATP-binding protein -
BC375_RS06860 (BC375_06400) 1380801..1381778 + 978 WP_046419683.1 hypothetical protein -
BC375_RS06865 (BC375_06405) 1382020..1382466 + 447 WP_031336674.1 hypothetical protein -
BC375_RS12840 (BC375_06410) 1382570..1382800 - 231 WP_010894096.1 hypothetical protein -
BC375_RS12845 1382782..1382964 - 183 WP_010894095.1 baseplate J/gp47 family protein -
BC375_RS06875 (BC375_06415) 1383067..1383363 + 297 WP_046419679.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BC375_RS06880 (BC375_06420) 1383366..1383659 + 294 WP_004085592.1 putative addiction module antidote protein Antitoxin
BC375_RS06885 (BC375_06425) 1383715..1384068 - 354 WP_046419676.1 hypothetical protein -
BC375_RS06890 (BC375_06430) 1384065..1384457 - 393 WP_230950027.1 Gp138 family membrane-puncturing spike protein -
BC375_RS06895 (BC375_06435) 1384983..1385999 + 1017 WP_060870179.1 M4 family metallopeptidase -
BC375_RS06900 (BC375_06440) 1385986..1386360 + 375 WP_060870180.1 hypothetical protein -
BC375_RS06905 (BC375_06445) 1386441..1386656 + 216 WP_230949859.1 helix-turn-helix domain-containing protein -
BC375_RS06910 (BC375_06450) 1386703..1387194 + 492 WP_230951054.1 DUF4065 domain-containing protein -
BC375_RS06915 (BC375_06455) 1387197..1387421 + 225 WP_230949856.1 hypothetical protein -
BC375_RS06920 (BC375_06460) 1387422..1388585 - 1164 WP_046419971.1 tail fiber protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1359018..1459171 100153


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(3-93)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11141.65 Da        Isoelectric Point: 9.8173

>T64854 WP_046419679.1 NZ_CP016610:1383067-1383363 [Xylella fastidiosa]
MIELKQTDTFRKWREKLKDARARSAIASRLDRLAFGHVGDAEPVGKGVSELRINYGPGYRVYFQQRGDTIYLLLCGGDKG
SQARDIKTALHLSEQWSE

Download         Length: 297 bp

>T64854 NZ_CP016610:1383067-1383363 [Xylella fastidiosa]
ATGATTGAATTGAAGCAGACTGACACCTTCCGCAAGTGGCGGGAGAAACTCAAGGATGCGCGCGCCCGCTCGGCCATCGC
CTCACGCCTCGACCGCTTGGCGTTCGGCCATGTCGGCGACGCCGAGCCAGTAGGGAAAGGTGTCAGCGAGCTTCGCATCA
ACTACGGCCCCGGTTACCGGGTGTATTTCCAGCAGCGTGGCGACACGATCTACTTGCTACTTTGCGGCGGTGACAAAGGA
TCACAAGCGCGTGACATCAAGACTGCGCTGCACCTCTCTGAACAATGGAGCGAATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10246.59 Da        Isoelectric Point: 5.6232

>AT64854 WP_004085592.1 NZ_CP016610:1383366-1383659 [Xylella fastidiosa]
MTEKLTSYDPAEDLTTDQAIADFMAAAFGTNDPAYVAHALGVVARAKGMTQIASQTGLSREQLYRSFSAEGNPTLRTTLA
VMKALGIELSAKPSGVH

Download         Length: 294 bp

>AT64854 NZ_CP016610:1383366-1383659 [Xylella fastidiosa]
ATGACCGAGAAACTGACGAGCTACGATCCGGCCGAGGACTTGACCACTGACCAGGCCATCGCCGATTTCATGGCAGCCGC
GTTCGGGACGAACGATCCTGCCTACGTTGCCCACGCGCTGGGCGTCGTTGCCCGCGCCAAGGGCATGACGCAGATCGCCA
GCCAGACAGGGCTATCGCGCGAACAGCTCTACCGCTCGTTCAGTGCCGAGGGCAACCCGACGCTGCGCACGACATTAGCC
GTGATGAAGGCGCTAGGGATCGAGCTCTCTGCGAAACCGTCTGGTGTTCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References