Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | PumAB/COG3657-dnstrm_HI1420 |
| Location | 1390256..1390848 | Replicon | chromosome |
| Accession | NZ_CP016608 | ||
| Organism | Xylella fastidiosa strain Salento-1 | ||
Toxin (Protein)
| Gene name | PumA | Uniprot ID | A0A060HCK8 |
| Locus tag | BCV75_RS06910 | Protein ID | WP_004085590.1 |
| Coordinates | 1390256..1390552 (+) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | PumB | Uniprot ID | - |
| Locus tag | BCV75_RS06915 | Protein ID | WP_004085592.1 |
| Coordinates | 1390555..1390848 (+) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BCV75_RS06875 (BCV75_06375) | 1385848..1386222 | + | 375 | WP_060870180.1 | hypothetical protein | - |
| BCV75_RS06880 (BCV75_06380) | 1386303..1386518 | + | 216 | WP_230949859.1 | helix-turn-helix domain-containing protein | - |
| BCV75_RS06885 (BCV75_06385) | 1386490..1387056 | + | 567 | WP_081089935.1 | DUF4065 domain-containing protein | - |
| BCV75_RS06890 (BCV75_06390) | 1387059..1387283 | + | 225 | WP_230949856.1 | hypothetical protein | - |
| BCV75_RS06895 (BCV75_06395) | 1387284..1388447 | - | 1164 | WP_046419971.1 | tail fiber protein | - |
| BCV75_RS06900 (BCV75_06400) | 1388451..1389011 | - | 561 | WP_046419969.1 | DUF2612 domain-containing protein | - |
| BCV75_RS06905 (BCV75_06405) | 1389008..1390153 | - | 1146 | WP_046419967.1 | baseplate J/gp47 family protein | - |
| BCV75_RS06910 (BCV75_06410) | 1390256..1390552 | + | 297 | WP_004085590.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| BCV75_RS06915 (BCV75_06415) | 1390555..1390848 | + | 294 | WP_004085592.1 | putative addiction module antidote protein | Antitoxin |
| BCV75_RS06920 (BCV75_06420) | 1390904..1391257 | - | 354 | WP_046419963.1 | hypothetical protein | - |
| BCV75_RS06925 (BCV75_06425) | 1391254..1391895 | - | 642 | WP_046419962.1 | Gp138 family membrane-puncturing spike protein | - |
| BCV75_RS06930 (BCV75_06430) | 1391892..1392722 | - | 831 | WP_046419672.1 | hypothetical protein | - |
| BCV75_RS06935 (BCV75_06435) | 1392719..1393036 | - | 318 | WP_046419669.1 | hypothetical protein | - |
| BCV75_RS12865 | 1393036..1393278 | - | 243 | WP_234048933.1 | hypothetical protein | - |
| BCV75_RS06940 (BCV75_06440) | 1393272..1393805 | - | 534 | WP_234048934.1 | hypothetical protein | - |
| BCV75_RS06945 (BCV75_06445) | 1394213..1394470 | - | 258 | WP_046419904.1 | Blp family class II bacteriocin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 1358881..1459027 | 100146 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11169.70 Da Isoelectric Point: 10.0610
>T64846 WP_004085590.1 NZ_CP016608:1390256-1390552 [Xylella fastidiosa]
MIELKQTDTFRKWREKLKDARARSAIASRLDRLAFGHVGDAEPVGKGVSELRINYGPGYRVYFQRRGDTIYLLLCGGDKG
SQARDIKTALHLSEQWSE
MIELKQTDTFRKWREKLKDARARSAIASRLDRLAFGHVGDAEPVGKGVSELRINYGPGYRVYFQRRGDTIYLLLCGGDKG
SQARDIKTALHLSEQWSE
Download Length: 297 bp
>T64846 NZ_CP016608:1390256-1390552 [Xylella fastidiosa]
ATGATTGAATTGAAGCAGACTGACACCTTCCGCAAGTGGCGGGAGAAACTCAAGGATGCGCGCGCCCGCTCGGCCATCGC
CTCGCGCCTCGACCGCTTGGCGTTCGGCCATGTCGGCGACGCGGAGCCAGTAGGGAAAGGTGTCAGCGAGCTTCGCATCA
ACTACGGCCCCGGTTACCGGGTGTATTTCCAGCGGCGTGGCGACACGATCTACTTGCTGCTTTGCGGCGGTGACAAAGGA
TCACAAGCGCGCGACATCAAGACTGCGCTGCACCTGTCTGAACAATGGAGCGAATGA
ATGATTGAATTGAAGCAGACTGACACCTTCCGCAAGTGGCGGGAGAAACTCAAGGATGCGCGCGCCCGCTCGGCCATCGC
CTCGCGCCTCGACCGCTTGGCGTTCGGCCATGTCGGCGACGCGGAGCCAGTAGGGAAAGGTGTCAGCGAGCTTCGCATCA
ACTACGGCCCCGGTTACCGGGTGTATTTCCAGCGGCGTGGCGACACGATCTACTTGCTGCTTTGCGGCGGTGACAAAGGA
TCACAAGCGCGCGACATCAAGACTGCGCTGCACCTGTCTGAACAATGGAGCGAATGA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10246.59 Da Isoelectric Point: 5.6232
>AT64846 WP_004085592.1 NZ_CP016608:1390555-1390848 [Xylella fastidiosa]
MTEKLTSYDPAEDLTTDQAIADFMAAAFGTNDPAYVAHALGVVARAKGMTQIASQTGLSREQLYRSFSAEGNPTLRTTLA
VMKALGIELSAKPSGVH
MTEKLTSYDPAEDLTTDQAIADFMAAAFGTNDPAYVAHALGVVARAKGMTQIASQTGLSREQLYRSFSAEGNPTLRTTLA
VMKALGIELSAKPSGVH
Download Length: 294 bp
>AT64846 NZ_CP016608:1390555-1390848 [Xylella fastidiosa]
ATGACCGAGAAACTGACGAGCTACGATCCAGCCGAGGACTTGACCACTGACCAGGCCATCGCCGATTTCATGGCAGCTGC
GTTCGGGACGAACGATCCTGCCTACGTTGCCCACGCGCTGGGCGTCGTTGCCCGCGCCAAGGGCATGACGCAGATCGCCA
GCCAAACAGGGCTATCGCGCGAACAGCTCTACCGCTCGTTCAGTGCCGAGGGCAACCCAACGCTGCGCACGACATTGGCC
GTGATGAAGGCGCTAGGGATCGAGCTGTCTGCGAAACCGTCGGGTGTTCACTGA
ATGACCGAGAAACTGACGAGCTACGATCCAGCCGAGGACTTGACCACTGACCAGGCCATCGCCGATTTCATGGCAGCTGC
GTTCGGGACGAACGATCCTGCCTACGTTGCCCACGCGCTGGGCGTCGTTGCCCGCGCCAAGGGCATGACGCAGATCGCCA
GCCAAACAGGGCTATCGCGCGAACAGCTCTACCGCTCGTTCAGTGCCGAGGGCAACCCAACGCTGCGCACGACATTGGCC
GTGATGAAGGCGCTAGGGATCGAGCTGTCTGCGAAACCGTCGGGTGTTCACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|