64845

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 1382929..1383521 Replicon chromosome
Accession NZ_CP016608
Organism Xylella fastidiosa strain Salento-1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag BCV75_RS06850 Protein ID WP_046419679.1
Coordinates 1382929..1383225 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag BCV75_RS06855 Protein ID WP_004085592.1
Coordinates 1383228..1383521 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BCV75_RS06820 (BCV75_06320) 1378467..1379045 - 579 WP_046419686.1 glutathione peroxidase -
BCV75_RS12340 1379411..1379572 - 162 WP_010894100.1 hypothetical protein -
BCV75_RS06830 (BCV75_06330) 1379791..1380666 + 876 WP_023906641.1 ABC transporter ATP-binding protein -
BCV75_RS06835 (BCV75_06335) 1380663..1381640 + 978 WP_046419683.1 hypothetical protein -
BCV75_RS06840 (BCV75_06340) 1381882..1382328 + 447 WP_031336674.1 hypothetical protein -
BCV75_RS12855 (BCV75_06345) 1382432..1382662 - 231 WP_010894096.1 hypothetical protein -
BCV75_RS12860 1382644..1382826 - 183 WP_010894095.1 baseplate J/gp47 family protein -
BCV75_RS06850 (BCV75_06350) 1382929..1383225 + 297 WP_046419679.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BCV75_RS06855 (BCV75_06355) 1383228..1383521 + 294 WP_004085592.1 putative addiction module antidote protein Antitoxin
BCV75_RS06860 (BCV75_06360) 1383577..1383930 - 354 WP_046419676.1 hypothetical protein -
BCV75_RS06865 (BCV75_06365) 1383927..1384319 - 393 WP_230950027.1 Gp138 family membrane-puncturing spike protein -
BCV75_RS06870 (BCV75_06370) 1384845..1385861 + 1017 WP_060870179.1 M4 family metallopeptidase -
BCV75_RS06875 (BCV75_06375) 1385848..1386222 + 375 WP_060870180.1 hypothetical protein -
BCV75_RS06880 (BCV75_06380) 1386303..1386518 + 216 WP_230949859.1 helix-turn-helix domain-containing protein -
BCV75_RS06885 (BCV75_06385) 1386490..1387056 + 567 WP_081089935.1 DUF4065 domain-containing protein -
BCV75_RS06890 (BCV75_06390) 1387059..1387283 + 225 WP_230949856.1 hypothetical protein -
BCV75_RS06895 (BCV75_06395) 1387284..1388447 - 1164 WP_046419971.1 tail fiber protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1358881..1459027 100146


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(3-93)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11141.65 Da        Isoelectric Point: 9.8173

>T64845 WP_046419679.1 NZ_CP016608:1382929-1383225 [Xylella fastidiosa]
MIELKQTDTFRKWREKLKDARARSAIASRLDRLAFGHVGDAEPVGKGVSELRINYGPGYRVYFQQRGDTIYLLLCGGDKG
SQARDIKTALHLSEQWSE

Download         Length: 297 bp

>T64845 NZ_CP016608:1382929-1383225 [Xylella fastidiosa]
ATGATTGAATTGAAGCAGACTGACACCTTCCGCAAGTGGCGGGAGAAACTCAAGGATGCGCGCGCCCGCTCGGCCATCGC
CTCACGCCTCGACCGCTTGGCGTTCGGCCATGTCGGCGACGCCGAGCCAGTAGGGAAAGGTGTCAGCGAGCTTCGCATCA
ACTACGGCCCCGGTTACCGGGTGTATTTCCAGCAGCGTGGCGACACGATCTACTTGCTACTTTGCGGCGGTGACAAAGGA
TCACAAGCGCGTGACATCAAGACTGCGCTGCACCTCTCTGAACAATGGAGCGAATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10246.59 Da        Isoelectric Point: 5.6232

>AT64845 WP_004085592.1 NZ_CP016608:1383228-1383521 [Xylella fastidiosa]
MTEKLTSYDPAEDLTTDQAIADFMAAAFGTNDPAYVAHALGVVARAKGMTQIASQTGLSREQLYRSFSAEGNPTLRTTLA
VMKALGIELSAKPSGVH

Download         Length: 294 bp

>AT64845 NZ_CP016608:1383228-1383521 [Xylella fastidiosa]
ATGACCGAGAAACTGACGAGCTACGATCCGGCCGAGGACTTGACCACTGACCAGGCCATCGCCGATTTCATGGCAGCCGC
GTTCGGGACGAACGATCCTGCCTACGTTGCCCACGCGCTGGGCGTCGTTGCCCGCGCCAAGGGCATGACGCAGATCGCCA
GCCAGACAGGGCTATCGCGCGAACAGCTCTACCGCTCGTTCAGTGCCGAGGGCAACCCGACGCTGCGCACGACATTAGCC
GTGATGAAGGCGCTAGGGATCGAGCTCTCTGCGAAACCGTCTGGTGTTCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References