Detailed information of TA system TA064842

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/RHH(antitoxin)
• Location: 982648..983149
• Replicon: chromosome
• Accession: NZ_CP016608
• Organism: Xylella fastidiosa strain Salento-1

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BCV75_RS04535
• Protein ID: WP_046420237.1
• Coordinates: 982853..983149 (+)
• Length: 99 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: BCV75_RS04530
• Protein ID: WP_230950355.1
• Coordinates: 982648..982860 (+)
• Length: 71 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BCV75_RS04490 (BCV75_04195)	978588..978848	+	261	WP_023906425.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	-
BCV75_RS04495 (BCV75_04200)	978835..979116	+	282	WP_060872372.1	type II toxin-antitoxin system YafQ family toxin	-
BCV75_RS04505 (BCV75_04205)	979534..980568	-	1035	WP_023906427.1	trypsin-like peptidase domain-containing protein	-
BCV75_RS04515 (BCV75_04215)	981351..981629	+	279	WP_010894528.1	CopG family ribbon-helix-helix protein	-
BCV75_RS04520 (BCV75_04220)	981617..981913	+	297	WP_010894527.1	type II toxin-antitoxin system RelE/ParE family toxin	-
BCV75_RS04530 (BCV75_04230)	982648..982860	+	213	WP_230950355.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
BCV75_RS04535 (BCV75_04235)	982853..983149	+	297	WP_046420237.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BCV75_RS12715 (BCV75_04240)	983610..983873	+	264	WP_023906433.1	hypothetical protein	-
BCV75_RS12720	983955..984044	+	90	WP_228762876.1	hypothetical protein	-
BCV75_RS04545 (BCV75_04245)	984453..984908	+	456	WP_046420235.1	hypothetical protein	-
BCV75_RS04550 (BCV75_04250)	984905..985177	+	273	WP_046420232.1	hypothetical protein	-
BCV75_RS04555 (BCV75_04255)	985181..985489	+	309	WP_010894519.1	type II toxin-antitoxin system RelE/ParE family toxin	-
BCV75_RS04560 (BCV75_04260)	985598..986122	+	525	WP_046420230.1	hypothetical protein	-
BCV75_RS04565 (BCV75_04265)	986116..986673	+	558	WP_046420226.1	recombinase family protein	-
BCV75_RS04570	986703..986912	-	210	WP_060872356.1	hypothetical protein	-
BCV75_RS04575 (BCV75_04270)	986929..988080	-	1152	Protein_844	toprim domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	986116..986673	557

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-93)

Antitoxin

• Antitoxin ParD (9-63)

Sequences

Toxin

Protein

• Length: 99 a.a.
• Molecular weight: 11418.96 Da
• Isoelectric Point: 6.8587

>T64842 WP_046420237.1 NZ_CP016608:982853-983149 [Xylella fastidiosa]
MAKSYRLTPLAEADLEEIWFYTFRHWSIGQADSYHRSLVAVFEGLAAGTKQGRPSVLPDFNKYLCGSCGSHVVYFMDYPD
HLDVIRILRQRQDTERYL

Nucleotide

• Length: 297 bp

>T64842 NZ_CP016608:982853-983149 [Xylella fastidiosa]
ATGGCTAAGTCCTATCGACTGACGCCGCTGGCCGAGGCCGATCTTGAAGAAATCTGGTTCTACACATTCAGGCACTGGTC
GATAGGGCAAGCCGACAGCTACCACCGCAGCCTAGTTGCGGTTTTCGAGGGGCTGGCAGCAGGTACAAAGCAAGGCCGCC
CTTCTGTTCTGCCGGACTTCAATAAATACCTATGTGGTTCATGTGGTTCGCATGTAGTGTATTTCATGGATTACCCCGAT
CACTTGGATGTTATCCGCATTCTGCGCCAGCGGCAGGATACCGAGCGGTACCTATAA

Antitoxin

Protein

• Length: 71 a.a.
• Molecular weight: 7557.38 Da
• Isoelectric Point: 6.8775

>AT64842 WP_230950355.1 NZ_CP016608:982648-982860 [Xylella fastidiosa]
MPSGSTSPAQVQGGRYGTASDVVRAGLRLLEEHETKVKALQDALNVGHQSGEPRPFDSEVFLSRMHTQHG

Nucleotide

• Length: 213 bp

>AT64842 NZ_CP016608:982648-982860 [Xylella fastidiosa]
TTGCCCTCGGGCAGCACTTCGCCAGCCCAAGTCCAGGGCGGTCGCTACGGTACCGCCAGCGATGTTGTCAGGGCCGGTCT
GCGGCTGCTGGAGGAACACGAAACAAAGGTGAAGGCGCTGCAAGATGCGCTGAATGTTGGCCACCAATCCGGCGAGCCGC
GCCCGTTCGACAGCGAGGTGTTTTTGAGCCGGATGCACACGCAGCATGGCTAA