Detailed information of TA system TA064817

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-DnaT
• Location: 22277..22799
• Replicon: plasmid pA3ES40_37
• Accession: NZ_CP016562
• Organism: Salmonella enterica subsp. enterica serovar Heidelberg strain A3ES40

Toxin (Protein)

• Gene name: relE
• Uniprot ID: G3CAN5
• Locus tag: BAX91_RS23080
• Protein ID: WP_000220560.1
• Coordinates: 22277..22558 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: G3CAG1
• Locus tag: BAX91_RS23085
• Protein ID: WP_000121743.1
• Coordinates: 22548..22799 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BAX91_RS23045	18125..19291	-	1167	WP_000539532.1	relaxase/mobilization nuclease domain-containing protein	-
BAX91_RS23050	19294..19839	-	546	WP_000757693.1	hypothetical protein	-
BAX91_RS25360	19834..19908	-	75	Protein_23	DNA distortion polypeptide 3	-
BAX91_RS24535	20165..20437	-	273	WP_000160399.1	hypothetical protein	-
BAX91_RS25250	20450..20647	-	198	WP_001675595.1	hypothetical protein	-
BAX91_RS24540	20669..20848	-	180	WP_000439078.1	hypothetical protein	-
BAX91_RS23060	20891..21220	-	330	WP_000866646.1	hypothetical protein	-
BAX91_RS23065	21313..21528	-	216	WP_001180116.1	hypothetical protein	-
BAX91_RS23070	21518..21763	-	246	WP_000356547.1	hypothetical protein	-
BAX91_RS23075	21808..22131	-	324	WP_001181903.1	hypothetical protein	-
BAX91_RS23080	22277..22558	-	282	WP_000220560.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BAX91_RS23085	22548..22799	-	252	WP_000121743.1	plasmid stabilization protein	Antitoxin
BAX91_RS23090	24033..24869	+	837	WP_001050931.1	replication initiation protein	-
BAX91_RS23095	24909..25355	+	447	WP_001074386.1	hypothetical protein	-
BAX91_RS23100	25423..25848	+	426	WP_000202944.1	hypothetical protein	-
BAX91_RS23105	25845..26822	-	978	WP_001269910.1	hypothetical protein	-
BAX91_RS23110	26847..27128	-	282	WP_001185482.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..37697	37697

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 13852.62 Da
• Isoelectric Point: 5.5500

>T64817 WP_000220560.1 NZ_CP016562:c22558-22277 [Salmonella enterica subsp. enterica serovar Heidelberg]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFF

Nucleotide

• Length: 282 bp

>T64817 NZ_CP016562:c22558-22277 [Salmonella enterica subsp. enterica serovar Heidelberg]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 12380.85 Da
• Isoelectric Point: 5.5500

>AT64817 WP_000121743.1 NZ_CP016562:c22799-22548 [Salmonella enterica subsp. enterica serovar Heidelberg]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFF

Nucleotide

• Length: 252 bp

>AT64817 NZ_CP016562:c22799-22548 [Salmonella enterica subsp. enterica serovar Heidelberg]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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Structures

Toxin

• AlphaFold DB: G3CAN5

Antitoxin

• AlphaFold DB: A0A3S5I301