Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4648671..4648942 Replicon chromosome
Accession NZ_CP016546
Organism Escherichia coli strain O177:H21

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4648801..4648904 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4648671..4648942 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BB405_RS23455 4645226..4645888 - 663 WP_000944256.1 exodeoxyribonuclease X -
BB405_RS23460 4645912..4646568 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein -
BB405_RS23465 4646670..4646900 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BB405_RS23470 4647039..4647413 + 375 WP_000204699.1 CopC domain-containing protein YobA -
BB405_RS23475 4647417..4648289 + 873 WP_000879285.1 copper homeostasis membrane protein CopD -
BB405_RS23480 4648302..4648643 + 342 WP_000976492.1 YebY family protein -
- 4648671..4648942 - 272 - - Antitoxin
- 4648801..4648904 + 104 - - Toxin
BB405_RS23490 4649039..4649695 + 657 WP_000812734.1 protein-serine/threonine phosphatase -
BB405_RS23495 4649696..4649887 - 192 WP_001296140.1 YebW family protein -
BB405_RS23500 4649992..4650228 - 237 WP_001295499.1 DUF1480 family protein -
BB405_RS23505 4650346..4651785 - 1440 WP_024190454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T64781 NZ_CP016546:4648801-4648904 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT64781 NZ_CP016546:c4648942-4648671 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References