Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1796631..1797113 Replicon chromosome
Accession NZ_CP016540
Organism Planococcus versutus strain L10.15

Toxin (Protein)


Gene name relE Uniprot ID A0A1B1S507
Locus tag I858_RS09250 Protein ID WP_065524628.1
Coordinates 1796850..1797113 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1B1S548
Locus tag I858_RS09245 Protein ID WP_065524629.1
Coordinates 1796631..1796843 (+) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I858_RS09225 1793028..1793582 + 555 WP_065524632.1 GNAT family N-acetyltransferase -
I858_RS09230 1793636..1793959 + 324 WP_065524631.1 ribonuclease E inhibitor RraB -
I858_RS17220 1794313..1795212 - 900 WP_065524630.1 hypothetical protein -
I858_RS09240 1795594..1796436 + 843 WP_065524931.1 hypothetical protein -
I858_RS09245 1796631..1796843 + 213 WP_065524629.1 CopG family transcriptional regulator Antitoxin
I858_RS09250 1796850..1797113 + 264 WP_065524628.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I858_RS09255 1797351..1797572 - 222 WP_065524627.1 RepB family plasmid replication initiator protein -
I858_RS17025 1797585..1797737 - 153 WP_157886512.1 hypothetical protein -
I858_RS16810 1797851..1798185 - 335 Protein_1767 ATP-binding protein -
I858_RS09265 1798301..1798555 - 255 WP_065524626.1 hypothetical protein -
I858_RS09270 1798579..1799472 - 894 WP_065524625.1 acyl-ACP desaturase -
I858_RS09285 1800951..1801502 + 552 WP_065524624.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1789365..1801502 12137


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(2-68)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10251.95 Da        Isoelectric Point: 9.8948

>T64762 WP_065524628.1 NZ_CP016540:1796850-1797113 [Planococcus versutus]
MYTVRFSEVALKKLKKMDRYQASLLVGWIEKNLNNCDDPRTQGKALVANHKGKWRYRVGDYRILALIEDEKIVITIIDVG
HRKDIYE

Download         Length: 264 bp

>T64762 NZ_CP016540:1796850-1797113 [Planococcus versutus]
ATGTATACTGTTCGATTCTCAGAAGTGGCATTGAAGAAATTAAAGAAAATGGATCGTTACCAGGCTTCCCTCTTGGTTGG
CTGGATTGAAAAGAATCTGAACAACTGTGACGACCCCAGAACTCAAGGGAAAGCATTAGTTGCAAATCACAAGGGAAAAT
GGCGTTACCGAGTAGGAGACTATCGCATACTGGCTTTAATTGAAGATGAAAAAATCGTCATCACCATCATTGATGTTGGA
CATCGCAAAGATATTTACGAATAA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8120.31 Da        Isoelectric Point: 4.8605

>AT64762 WP_065524629.1 NZ_CP016540:1796631-1796843 [Planococcus versutus]
VATISLRVDERDSKLIRDYAKLKKTSVSDLMRNAIIEKIEDEIDLEHFDRVLANVEKTYSLDEVKKELGL

Download         Length: 213 bp

>AT64762 NZ_CP016540:1796631-1796843 [Planococcus versutus]
GTGGCTACTATTTCCTTGCGTGTAGATGAACGTGACAGTAAATTGATTCGTGATTATGCCAAATTAAAAAAGACATCTGT
TTCTGATTTAATGAGAAATGCCATCATTGAAAAGATTGAAGATGAAATCGATTTAGAGCATTTTGATCGTGTCCTGGCAA
ATGTGGAAAAAACCTATTCATTGGATGAAGTCAAAAAAGAGCTCGGTTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B1S507

Antitoxin

Source ID Structure
AlphaFold DB A0A1B1S548

References