Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2394..2953 Replicon plasmid pCE-R2-11-0435_92
Accession NZ_CP016520
Organism Salmonella enterica subsp. enterica serovar Heidelberg strain CE-R2-11-0435

Toxin (Protein)


Gene name relE Uniprot ID A0A733EV64
Locus tag BAT85_RS23185 Protein ID WP_001582571.1
Coordinates 2678..2953 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C1J8K5
Locus tag BAT85_RS23180 Protein ID WP_001178089.1
Coordinates 2394..2678 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BAT85_RS23175 455..1486 + 1032 WP_000907861.1 replication initiation protein -
BAT85_RS23180 2394..2678 + 285 WP_001178089.1 ribbon-helix-helix protein, CopG family Antitoxin
BAT85_RS23185 2678..2953 + 276 WP_001582571.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BAT85_RS23190 3059..3337 + 279 WP_001105069.1 hypothetical protein -
BAT85_RS23195 3532..3798 - 267 WP_000627829.1 hypothetical protein -
BAT85_RS23200 3798..4292 - 495 WP_001582574.1 hypothetical protein -
BAT85_RS23205 4348..4950 - 603 WP_000517695.1 hypothetical protein -
BAT85_RS23210 5304..6719 + 1416 WP_029397060.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..92323 92323


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Bacterioopsin activator-type, HTH domain

(147-197)

Antitoxin

Protein of unknown function DUF488

(3-108)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 11810.03 Da        Isoelectric Point: 12.7590

>T64752 WP_001582571.1 NZ_CP016520:2678-2953 [Salmonella enterica subsp. enterica serovar Heidelberg]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKK

Download         Length: 276 bp

>T64752 NZ_CP016520:2678-2953 [Salmonella enterica subsp. enterica serovar Heidelberg]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 12194.55 Da        Isoelectric Point: 12.7731

>AT64752 WP_001178089.1 NZ_CP016520:2394-2678 [Salmonella enterica subsp. enterica serovar Heidelberg]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKK

Download         Length: 285 bp

>AT64752 NZ_CP016520:2394-2678 [Salmonella enterica subsp. enterica serovar Heidelberg]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A733EV64

Antitoxin

Source ID Structure
AlphaFold DB A0A731IHA8

References