Detailed information of TA system TA064742

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 4450202..4450872
• Replicon: chromosome
• Accession: NZ_CP016499
• Organism: Agrobacterium sp. RAC06

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BSY240_RS21095
• Protein ID: WP_083229691.1
• Coordinates: 4450202..4450462 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A0N1L8F5
• Locus tag: BSY240_RS21100
• Protein ID: WP_054148478.1
• Coordinates: 4450462..4450872 (+)
• Length: 137 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSY240_RS21075	4445345..4445710	+	366	WP_210183776.1	c-type cytochrome	-
BSY240_RS21080	4445915..4447003	+	1089	WP_069043620.1	hypothetical protein	-
BSY240_RS21085	4447083..4448234	+	1152	WP_069043621.1	hypothetical protein	-
BSY240_RS21090	4448237..4450150	+	1914	WP_069043622.1	AAA family ATPase	-
BSY240_RS21095	4450202..4450462	+	261	WP_083229691.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BSY240_RS21100	4450462..4450872	+	411	WP_054148478.1	helix-turn-helix transcriptional regulator	Antitoxin
BSY240_RS21105	4450869..4452164	+	1296	WP_069043623.1	hypothetical protein	-
BSY240_RS21110	4452157..4453266	+	1110	WP_069043624.1	DUF2333 family protein	-
BSY240_RS21115	4453304..4453996	-	693	WP_054148539.1	LuxR family transcriptional regulator	-
BSY240_RS21120	4454176..4454640	-	465	WP_069043626.1	Lrp/AsnC ligand binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-82)

Antitoxin

• Cro/C1-type helix-turn-helix domain (76-123)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 9899.29 Da
• Isoelectric Point: 10.6564

>T64742 WP_083229691.1 NZ_CP016499:4450202-4450462 [Agrobacterium sp. RAC06]
VRDVVYSKDAIRSLNRMPANEARRIRSKVLQYAADPASLANNVKKLRDSRYHRLRIGDWRVIFREDGTVVDVVRVAARGE
AYEGEL

Nucleotide

• Length: 261 bp

>T64742 NZ_CP016499:4450202-4450462 [Agrobacterium sp. RAC06]
GTGCGGGACGTTGTTTACAGCAAGGATGCCATTCGTAGCTTGAACCGGATGCCGGCAAACGAGGCGCGACGTATCCGGTC
TAAGGTTCTTCAGTATGCCGCCGACCCGGCTTCACTCGCCAACAATGTCAAAAAGTTACGTGACAGCCGTTACCATCGCC
TGCGGATCGGGGACTGGCGCGTGATCTTCCGTGAAGACGGAACCGTCGTCGACGTGGTGCGTGTGGCAGCACGCGGTGAA
GCCTATGAGGGAGAGCTCTGA

Antitoxin

Protein

• Length: 137 a.a.
• Molecular weight: 15053.98 Da
• Isoelectric Point: 4.2841

>AT64742 WP_054148478.1 NZ_CP016499:4450462-4450872 [Agrobacterium sp. RAC06]
MTIASSFTTPNGEEMIVLSRKDYEALIERIEDLEDSLAVVGFERKLAAGEEELIPAEYVNRMGEGESPIRVWRDFRGMAA
KDLAAAAGISTAYLSEIETGKKDGSVATLKAIADVLKLDLDDLYWRHEDRKVTDTA

Nucleotide

• Length: 411 bp

>AT64742 NZ_CP016499:4450462-4450872 [Agrobacterium sp. RAC06]
ATGACGATCGCATCATCGTTTACGACGCCAAATGGCGAAGAGATGATCGTACTCAGCCGCAAAGACTACGAAGCACTGAT
CGAGCGCATCGAGGATCTGGAAGACAGTCTGGCTGTCGTTGGTTTCGAGAGGAAGCTAGCTGCGGGCGAGGAAGAGCTGA
TCCCTGCCGAGTACGTCAACCGGATGGGTGAAGGTGAAAGCCCGATCCGCGTCTGGCGCGATTTTCGCGGTATGGCGGCC
AAGGACCTTGCTGCCGCTGCCGGAATCAGCACCGCTTATCTGTCCGAGATCGAAACAGGCAAGAAGGACGGCAGTGTCGC
AACACTCAAAGCGATCGCCGATGTCTTGAAGCTCGACCTCGATGACCTTTACTGGCGGCACGAGGACAGGAAGGTCACAG
ATACCGCATGA

Structures

Antitoxin

• AlphaFold DB: A0A0N1L8F5