Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3178023..3178444 Replicon chromosome
Accession NZ_CP016499
Organism Agrobacterium sp. RAC06

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BSY240_RS23715 Protein ID WP_082347715.1
Coordinates 3178268..3178444 (+) Length 59 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A0N1L568
Locus tag BSY240_RS15255 Protein ID WP_054150438.1
Coordinates 3178023..3178271 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY240_RS15225 3173311..3173613 + 303 WP_069042854.1 4a-hydroxytetrahydrobiopterin dehydratase -
BSY240_RS15230 3173683..3174063 + 381 WP_054150354.1 DUF1232 domain-containing protein -
BSY240_RS15235 3174329..3174832 + 504 WP_054150436.1 hypothetical protein -
BSY240_RS15240 3175070..3176308 + 1239 WP_150127479.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
BSY240_RS15245 3176342..3176983 - 642 WP_054150355.1 LysE family translocator -
BSY240_RS15250 3177058..3177921 - 864 WP_054150356.1 SDR family NAD(P)-dependent oxidoreductase -
BSY240_RS15255 3178023..3178271 + 249 WP_054150438.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
BSY240_RS23715 3178268..3178444 + 177 WP_082347715.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSY240_RS15260 3178665..3179888 + 1224 WP_069042855.1 argininosuccinate synthase -
BSY240_RS15265 3179943..3181133 - 1191 WP_069042856.1 multidrug effflux MFS transporter -
BSY240_RS15270 3181242..3181670 - 429 WP_069042857.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-53)

Antitoxin

Antitoxin ParD

(5-72)


Sequences

Toxin        


Download         Length: 59 a.a.        Molecular weight: 6743.77 Da        Isoelectric Point: 9.0187

>T64740 WP_082347715.1 NZ_CP016499:3178268-3178444 [Agrobacterium sp. RAC06]
MKPLIVSPRAAHDLDALFDYTEERWGLDQAIAYTLGIRRNLQEICEGRRYGRKIPGLR

Download         Length: 177 bp

>T64740 NZ_CP016499:3178268-3178444 [Agrobacterium sp. RAC06]
ATGAAGCCCCTGATTGTTTCGCCGCGGGCTGCTCACGACCTCGACGCGCTCTTCGACTACACCGAAGAGCGTTGGGGTTT
GGATCAGGCGATTGCATACACGCTTGGGATCAGGCGCAACCTTCAAGAAATCTGCGAGGGACGACGCTATGGCCGGAAAA
TTCCCGGACTTAGGTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8804.71 Da        Isoelectric Point: 3.8597

>AT64740 WP_054150438.1 NZ_CP016499:3178023-3178271 [Agrobacterium sp. RAC06]
MNKFTTVTVSGELAEFIEAKISAGDYASEAEVIEAALALLRDEVDGLAAIQAAIDEGEASGQPQPFDFDEFIDRKPRRSA
AE

Download         Length: 249 bp

>AT64740 NZ_CP016499:3178023-3178271 [Agrobacterium sp. RAC06]
ATGAACAAGTTTACGACCGTCACGGTCTCGGGGGAACTGGCGGAGTTCATCGAAGCCAAAATTTCTGCTGGAGATTATGC
CTCGGAAGCCGAGGTCATTGAGGCTGCCCTCGCATTGCTGCGCGATGAGGTGGATGGCCTGGCCGCTATCCAGGCTGCTA
TCGATGAGGGTGAGGCCTCTGGTCAGCCGCAGCCGTTTGACTTTGATGAGTTCATCGATCGCAAGCCTCGCCGCTCCGCC
GCCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0N1L568

References