Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 1771789..1772332 Replicon chromosome
Accession NZ_CP016499
Organism Agrobacterium sp. RAC06

Toxin (Protein)


Gene name parE Uniprot ID A0A1B3P159
Locus tag BSY240_RS08665 Protein ID WP_069042023.1
Coordinates 1771789..1772088 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A0N0JM82
Locus tag BSY240_RS08670 Protein ID WP_054148857.1
Coordinates 1772081..1772332 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY240_RS08645 1767287..1768558 + 1272 WP_069042019.1 phosphoribosylamine--glycine ligase -
BSY240_RS08650 1768684..1769133 + 450 WP_069042020.1 hypothetical protein -
BSY240_RS08655 1769410..1771230 + 1821 WP_069042021.1 cache domain-containing protein -
BSY240_RS08660 1771289..1771792 - 504 WP_069042022.1 DUF523 domain-containing protein -
BSY240_RS08665 1771789..1772088 - 300 WP_069042023.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSY240_RS08670 1772081..1772332 - 252 WP_054148857.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
BSY240_RS08675 1772438..1774591 - 2154 WP_069042024.1 glycine--tRNA ligase subunit beta -
BSY240_RS08680 1774763..1776697 - 1935 WP_069042025.1 DUF2207 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-93)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11561.23 Da        Isoelectric Point: 6.7199

>T64739 WP_069042023.1 NZ_CP016499:c1772088-1771789 [Agrobacterium sp. RAC06]
VAEIRLSPAARQDFLEIGDYTRDRWSEAQAERYLRQILAMIGEIGVHPFLGSEVRSLRPGYRRRRCGSHLIFYVILEDSM
VEVVRIIHERADYLGKLDD

Download         Length: 300 bp

>T64739 NZ_CP016499:c1772088-1771789 [Agrobacterium sp. RAC06]
GTGGCTGAGATCCGGCTCAGTCCGGCCGCACGCCAGGATTTTCTCGAAATCGGTGACTACACGCGGGATCGATGGTCTGA
GGCTCAAGCCGAGCGATACCTCAGGCAGATCCTTGCGATGATCGGGGAAATCGGAGTCCATCCGTTTTTAGGCAGCGAGG
TACGTTCATTGCGGCCTGGTTACCGCCGCAGGCGTTGCGGCTCACATCTGATCTTCTACGTCATTCTGGAGGATAGCATG
GTGGAAGTTGTGCGCATCATTCACGAGCGAGCCGACTATCTGGGTAAACTGGACGACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9351.44 Da        Isoelectric Point: 4.2472

>AT64739 WP_054148857.1 NZ_CP016499:c1772332-1772081 [Agrobacterium sp. RAC06]
MNKPVQVTIAEPFDSFIDAQLESGQFKSAQEVVEAGLQLLKEEQARVEWLRNALIEGENSGPSVSFDPEDLMTSVRERWK
SRG

Download         Length: 252 bp

>AT64739 NZ_CP016499:c1772332-1772081 [Agrobacterium sp. RAC06]
ATGAACAAGCCCGTCCAGGTGACCATCGCTGAGCCCTTTGACAGCTTCATCGACGCCCAGCTCGAAAGCGGCCAGTTTAA
GTCGGCGCAAGAGGTGGTCGAAGCCGGTCTGCAGCTTTTGAAGGAGGAGCAGGCCAGGGTCGAATGGCTGCGCAACGCGC
TGATCGAGGGGGAAAACAGTGGGCCCTCCGTTTCTTTCGATCCAGAAGATCTCATGACTTCCGTTCGCGAAAGATGGAAA
AGCCGTGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B3P159

Antitoxin

Source ID Structure
AlphaFold DB A0A0N0JM82

References