Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 931351..931856 Replicon chromosome
Accession NZ_CP016499
Organism Agrobacterium sp. RAC06

Toxin (Protein)


Gene name relE Uniprot ID A0A1B3P4C0
Locus tag BSY240_RS04410 Protein ID WP_069041535.1
Coordinates 931602..931856 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID A0A0N1L550
Locus tag BSY240_RS04405 Protein ID WP_054150137.1
Coordinates 931351..931605 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY240_RS04370 927328..927996 - 669 WP_069041532.1 protein-L-isoaspartate O-methyltransferase -
BSY240_RS04380 928411..928635 - 225 WP_150127398.1 hypothetical protein -
BSY240_RS04385 928791..929072 - 282 WP_069041534.1 hypothetical protein -
BSY240_RS04395 929482..929706 + 225 WP_054150124.1 hypothetical protein -
BSY240_RS04400 929815..931260 + 1446 WP_069043822.1 DNA photolyase family protein -
BSY240_RS04405 931351..931605 + 255 WP_054150137.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BSY240_RS04410 931602..931856 + 255 WP_069041535.1 Txe/YoeB family addiction module toxin Toxin
BSY240_RS04415 931976..932230 + 255 WP_054150122.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
BSY240_RS04420 932223..932669 + 447 WP_069041536.1 type II toxin-antitoxin system VapC family toxin -
BSY240_RS04425 932878..933915 + 1038 WP_069041537.1 cysteine synthase A -
BSY240_RS04430 933936..934667 + 732 WP_069041538.1 alanyl-tRNA editing protein -
BSY240_RS04435 934694..936118 + 1425 WP_069041539.1 3-mercaptopyruvate sulfurtransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10080.58 Da        Isoelectric Point: 10.1382

>T64736 WP_069041535.1 NZ_CP016499:931602-931856 [Agrobacterium sp. RAC06]
VKLIFHARAWEDYLYWQSTDPKMLARVNQLIKDSSRSPFHGIGKPEPLRGELRGWLSRRIDQEHRLVYRPKEDGLLIAQC
RHHY

Download         Length: 255 bp

>T64736 NZ_CP016499:931602-931856 [Agrobacterium sp. RAC06]
GTGAAGCTCATCTTCCATGCGCGTGCCTGGGAGGACTACCTGTATTGGCAGTCTACCGATCCGAAGATGCTGGCGCGCGT
CAATCAATTGATCAAGGACAGCAGCCGATCACCCTTTCATGGCATCGGCAAACCGGAGCCGCTGCGGGGCGAGTTGCGCG
GCTGGTTGTCGCGGCGGATCGATCAGGAGCATCGGCTCGTCTATCGTCCGAAGGAAGACGGGCTCCTGATCGCGCAGTGC
CGCCATCACTACTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9492.62 Da        Isoelectric Point: 4.7037

>AT64736 WP_054150137.1 NZ_CP016499:931351-931605 [Agrobacterium sp. RAC06]
MRTTSYSDLRKNLASLLDSVTEDRTPVLITRDRGKPAAVLMSVEDFASYEETQHLLKSPRNAERLLEAVRDLDEGKGEAR
ELSE

Download         Length: 255 bp

>AT64736 NZ_CP016499:931351-931605 [Agrobacterium sp. RAC06]
ATGAGAACGACATCCTACAGCGACCTGCGCAAGAACCTGGCCTCTCTGCTCGACAGCGTGACTGAGGACCGGACGCCTGT
GCTGATCACCCGTGATCGCGGAAAACCAGCTGCCGTTCTGATGTCGGTGGAGGATTTTGCGTCCTATGAGGAAACGCAGC
ATCTCCTAAAGAGCCCCCGCAACGCCGAACGCCTGCTTGAAGCGGTGCGGGACCTCGATGAAGGCAAGGGCGAGGCGCGC
GAGCTCTCGGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B3P4C0

Antitoxin

Source ID Structure
AlphaFold DB A0A0N1L550

References