Detailed information of TA system TA064672

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 3199910..3200483
• Replicon: chromosome
• Accession: NZ_CP016464
• Organism: Bosea sp. RAC05

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BSY19_RS18580
• Protein ID: WP_069055438.1
• Coordinates: 3200238..3200483 (+)
• Length: 82 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BSY19_RS18575
• Protein ID: WP_069057235.1
• Coordinates: 3199910..3200209 (+)
• Length: 100 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BSY19_RS18565	3196769..3198526	+	1758	WP_069055436.1	AsmA family protein	-
BSY19_RS18570	3198670..3199818	+	1149	WP_069055437.1	homoserine O-acetyltransferase	-
BSY19_RS18575	3199910..3200209	+	300	WP_069057235.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
BSY19_RS18580	3200238..3200483	+	246	WP_069055438.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BSY19_RS18585	3200505..3201137	-	633	WP_069055439.1	MarC family protein	-
BSY19_RS18590	3201636..3204347	+	2712	WP_150129804.1	DNA gyrase subunit A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-76)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-68)

Sequences

Toxin

Protein

• Length: 82 a.a.
• Molecular weight: 8939.15 Da
• Isoelectric Point: 7.0094

>T64672 WP_069055438.1 NZ_CP016464:3200238-3200483 [Bosea sp. RAC05]
MSIVGYIADDNPDAAQRLKDEIEARVAKLIAFPDRFRPGRVEGTREMSVGPNYVVVYATGGATIRILRGLHAARQWPPDS
D

Nucleotide

• Length: 246 bp

>T64672 NZ_CP016464:3200238-3200483 [Bosea sp. RAC05]
ATGTCGATCGTCGGTTACATCGCCGACGACAACCCGGATGCTGCTCAGCGGCTGAAGGACGAGATCGAAGCGAGAGTGGC
GAAGCTGATCGCATTCCCCGACCGATTTCGCCCCGGGCGCGTTGAAGGCACCCGCGAAATGAGCGTCGGGCCGAACTACG
TCGTCGTCTATGCTACCGGTGGCGCCACCATCCGCATCCTGAGGGGGTTGCACGCCGCCCGGCAATGGCCCCCGGACAGC
GACTAG

Antitoxin

Protein

• Length: 100 a.a.
• Molecular weight: 10694.28 Da
• Isoelectric Point: 6.2227

>AT64672 WP_069057235.1 NZ_CP016464:3199910-3200209 [Bosea sp. RAC05]
VAARTSMLHVRIDDQLKAEATETLAGFGLSVSDAVRILLTRVVKEGGLPAGLAVDPEAHDLWFRAKVREALADPAPGLSH
DQVMDDVQALIDRKRLARA

Nucleotide

• Length: 300 bp

>AT64672 NZ_CP016464:3199910-3200209 [Bosea sp. RAC05]
GTGGCCGCACGAACCTCGATGTTGCATGTCCGAATCGACGATCAGCTCAAGGCCGAGGCCACGGAAACGCTCGCAGGTTT
CGGTCTGTCCGTTTCTGATGCAGTCCGGATCCTGCTGACCCGCGTGGTGAAGGAAGGCGGCCTGCCGGCAGGGCTGGCCG
TCGATCCGGAGGCGCATGACCTCTGGTTTCGGGCCAAGGTTCGCGAGGCCCTGGCCGACCCGGCGCCTGGCCTGTCGCAT
GATCAGGTCATGGACGATGTTCAAGCGCTGATCGACAGGAAGCGTCTTGCCAGGGCCTGA