Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mazEF/PemK-MazE |
Location | 2331154..2331698 | Replicon | chromosome |
Accession | NZ_CP016464 | ||
Organism | Bosea sp. RAC05 |
Toxin (Protein)
Gene name | mazF | Uniprot ID | A0A1B3NRD9 |
Locus tag | BSY19_RS14495 | Protein ID | WP_069054780.1 |
Coordinates | 2331154..2331477 (-) | Length | 108 a.a. |
Antitoxin (Protein)
Gene name | mazE | Uniprot ID | A0A1B3NKU5 |
Locus tag | BSY19_RS14500 | Protein ID | WP_069054781.1 |
Coordinates | 2331474..2331698 (-) | Length | 75 a.a. |
Genomic Context
Location: 2326833..2327888 (1056 bp)
Type: Others
Protein ID: WP_069054777.1
Type: Others
Protein ID: WP_069054777.1
Location: 2327893..2328342 (450 bp)
Type: Others
Protein ID: WP_069054778.1
Type: Others
Protein ID: WP_069054778.1
Location: 2328546..2329058 (513 bp)
Type: Others
Protein ID: WP_069054779.1
Type: Others
Protein ID: WP_069054779.1
Location: 2329333..2330565 (1233 bp)
Type: Others
Protein ID: WP_069057115.1
Type: Others
Protein ID: WP_069057115.1
Location: 2333173..2334474 (1302 bp)
Type: Others
Protein ID: WP_069057117.1
Type: Others
Protein ID: WP_069057117.1
Location: 2334531..2334764 (234 bp)
Type: Others
Protein ID: WP_150129626.1
Type: Others
Protein ID: WP_150129626.1
Location: 2334766..2335209 (444 bp)
Type: Others
Protein ID: WP_171905145.1
Type: Others
Protein ID: WP_171905145.1
Location: 2335229..2335726 (498 bp)
Type: Others
Protein ID: WP_069054784.1
Type: Others
Protein ID: WP_069054784.1
Location: 2331154..2331477 (324 bp)
Type: Toxin
Protein ID: WP_069054780.1
Type: Toxin
Protein ID: WP_069054780.1
Location: 2331474..2331698 (225 bp)
Type: Antitoxin
Protein ID: WP_069054781.1
Type: Antitoxin
Protein ID: WP_069054781.1
Location: 2331773..2332963 (1191 bp)
Type: Others
Protein ID: WP_069057116.1
Type: Others
Protein ID: WP_069057116.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BSY19_RS14475 | 2326833..2327888 | + | 1056 | WP_069054777.1 | enoyl-CoA hydratase/isomerase family protein | - |
BSY19_RS14480 | 2327893..2328342 | + | 450 | WP_069054778.1 | hypothetical protein | - |
BSY19_RS14485 | 2328546..2329058 | + | 513 | WP_069054779.1 | winged helix DNA-binding protein | - |
BSY19_RS14490 | 2329333..2330565 | + | 1233 | WP_069057115.1 | L,D-transpeptidase family protein | - |
BSY19_RS14495 | 2331154..2331477 | - | 324 | WP_069054780.1 | type II toxin-antitoxin system PemK/MazF family toxin | Toxin |
BSY19_RS14500 | 2331474..2331698 | - | 225 | WP_069054781.1 | antitoxin MazE family protein | Antitoxin |
BSY19_RS14505 | 2331773..2332963 | - | 1191 | WP_069057116.1 | Na+/H+ antiporter NhaA | - |
BSY19_RS14510 | 2333173..2334474 | + | 1302 | WP_069057117.1 | serine hydroxymethyltransferase | - |
BSY19_RS14515 | 2334531..2334764 | + | 234 | WP_150129626.1 | hypothetical protein | - |
BSY19_RS14520 | 2334766..2335209 | + | 444 | WP_171905145.1 | hypothetical protein | - |
BSY19_RS14525 | 2335229..2335726 | + | 498 | WP_069054784.1 | transcriptional regulator NrdR | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 108 a.a. Molecular weight: 11383.37 Da Isoelectric Point: 10.4581
>T64671 WP_069054780.1 NZ_CP016464:c2331477-2331154 [Bosea sp. RAC05]
VTRGEIVTVAMTGDFGKPRPALVVHADPFDQTGTITVLLISGTLVDAPLIRLTVQPTPQNGLLKPSQIQIDKAMSVQRHR
VGAVIGRLDDTTMLAVTRSLALFLGIA
VTRGEIVTVAMTGDFGKPRPALVVHADPFDQTGTITVLLISGTLVDAPLIRLTVQPTPQNGLLKPSQIQIDKAMSVQRHR
VGAVIGRLDDTTMLAVTRSLALFLGIA
Download Length: 324 bp
>T64671 NZ_CP016464:c2331477-2331154 [Bosea sp. RAC05]
GTGACGCGTGGCGAGATCGTCACCGTCGCGATGACGGGCGATTTCGGAAAGCCCCGCCCTGCCCTCGTCGTCCATGCCGA
TCCTTTCGATCAGACCGGCACCATCACCGTTCTGCTGATCTCGGGAACGCTGGTCGATGCCCCCCTGATCCGCCTGACAG
TCCAGCCGACCCCACAGAACGGACTGCTCAAACCCTCGCAGATCCAGATCGACAAGGCGATGTCGGTCCAGCGGCACAGG
GTCGGCGCCGTCATAGGAAGACTGGACGATACGACCATGCTGGCGGTGACGCGGTCACTGGCGCTGTTTCTCGGGATTGC
GTGA
GTGACGCGTGGCGAGATCGTCACCGTCGCGATGACGGGCGATTTCGGAAAGCCCCGCCCTGCCCTCGTCGTCCATGCCGA
TCCTTTCGATCAGACCGGCACCATCACCGTTCTGCTGATCTCGGGAACGCTGGTCGATGCCCCCCTGATCCGCCTGACAG
TCCAGCCGACCCCACAGAACGGACTGCTCAAACCCTCGCAGATCCAGATCGACAAGGCGATGTCGGTCCAGCGGCACAGG
GTCGGCGCCGTCATAGGAAGACTGGACGATACGACCATGCTGGCGGTGACGCGGTCACTGGCGCTGTTTCTCGGGATTGC
GTGA
Antitoxin
Download Length: 75 a.a. Molecular weight: 8159.17 Da Isoelectric Point: 4.7085
>AT64671 WP_069054781.1 NZ_CP016464:c2331698-2331474 [Bosea sp. RAC05]
MPTPVNQRVQKRRDALRAAGLRPVQIWVPDTRRPGFVEECRRQSLIVAAADADDNGLNSFLEAALADLTGEDEA
MPTPVNQRVQKRRDALRAAGLRPVQIWVPDTRRPGFVEECRRQSLIVAAADADDNGLNSFLEAALADLTGEDEA
Download Length: 225 bp
>AT64671 NZ_CP016464:c2331698-2331474 [Bosea sp. RAC05]
ATGCCCACACCCGTCAACCAGCGGGTTCAGAAGCGTCGCGATGCGCTGCGGGCCGCCGGGCTGCGGCCCGTTCAGATTTG
GGTTCCAGACACCCGCCGTCCGGGTTTTGTCGAAGAGTGCCGCCGTCAGTCGCTCATTGTCGCAGCGGCGGACGCCGACG
ATAACGGCCTGAACAGCTTTCTCGAGGCCGCTCTGGCCGATCTCACCGGCGAGGACGAGGCGTGA
ATGCCCACACCCGTCAACCAGCGGGTTCAGAAGCGTCGCGATGCGCTGCGGGCCGCCGGGCTGCGGCCCGTTCAGATTTG
GGTTCCAGACACCCGCCGTCCGGGTTTTGTCGAAGAGTGCCGCCGTCAGTCGCTCATTGTCGCAGCGGCGGACGCCGACG
ATAACGGCCTGAACAGCTTTCTCGAGGCCGCTCTGGCCGATCTCACCGGCGAGGACGAGGCGTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1B3NRD9 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1B3NKU5 |