Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 2014056..2014527 Replicon chromosome
Accession NZ_CP016464
Organism Bosea sp. RAC05

Toxin (Protein)


Gene name - Uniprot ID A0A1B3NJT5
Locus tag BSY19_RS12970 Protein ID WP_069054534.1
Coordinates 2014056..2014319 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1B3NJU0
Locus tag BSY19_RS12975 Protein ID WP_069054535.1
Coordinates 2014306..2014527 (+) Length 74 a.a.

Genomic Context

BSY19_RS12945BSY19_RS12950BSY19_RS12965BSY19_RS12970BSY19_RS12975BSY19_RS12990BSY19_RS12995BSY19_RS13000BSY19_RS12955BSY19_RS27015BSY19_RS12960BSY19_RS12980BSY19_RS12985
Location: 2010144..2010977 (834 bp)
Type: Others
Protein ID: WP_069054531.1
Location: 2011075..2011485 (411 bp)
Type: Others
Protein ID: WP_083247911.1
Location: 2012966..2013985 (1020 bp)
Type: Others
Protein ID: WP_069054533.1
Location: 2014056..2014319 (264 bp)
Type: Toxin
Protein ID: WP_069054534.1
Location: 2014306..2014527 (222 bp)
Type: Antitoxin
Protein ID: WP_069054535.1
Location: 2017415..2017966 (552 bp)
Type: Others
Protein ID: WP_150129603.1
Location: 2018070..2018681 (612 bp)
Type: Others
Protein ID: WP_069057065.1
Location: 2018681..2019151 (471 bp)
Type: Others
Protein ID: WP_069054538.1
Location: 2011514..2011756 (243 bp)
Type: Others
Protein ID: WP_083247576.1
Location: 2011821..2012000 (180 bp)
Type: Others
Protein ID: WP_083247912.1
Location: 2012006..2012884 (879 bp)
Type: Others
Protein ID: WP_069054532.1
Location: 2014595..2015716 (1122 bp)
Type: Others
Protein ID: WP_083247577.1
Location: 2015811..2017328 (1518 bp)
Type: Others
Protein ID: WP_069054537.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
BSY19_RS129452010144..2010977+834WP_069054531.1sulfite exporter TauE/SafE family protein-
BSY19_RS129502011075..2011485+411WP_083247911.1GNAT family N-acetyltransferase-
BSY19_RS129552011514..2011756-243WP_083247576.1hypothetical protein-
BSY19_RS270152011821..2012000-180WP_083247912.1DUF1289 domain-containing protein-
BSY19_RS129602012006..2012884-879WP_069054532.1adenosylcobinamide-GDP ribazoletransferase-
BSY19_RS129652012966..2013985+1020WP_069054533.1nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase-
BSY19_RS129702014056..2014319+264WP_069054534.1BrnT family toxinToxin
BSY19_RS129752014306..2014527+222WP_069054535.1CopG family transcriptional regulatorAntitoxin
BSY19_RS129802014595..2015716-1122WP_083247577.1D-alanine--D-alanine ligase-
BSY19_RS129852015811..2017328-1518WP_069054537.1HAMP domain-containing histidine kinase-
BSY19_RS129902017415..2017966+552WP_150129603.1thermonuclease family protein-
BSY19_RS129952018070..2018681+612WP_069057065.1glutathione S-transferase family protein-
BSY19_RS130002018681..2019151+471WP_069054538.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10038.36 Da        Isoelectric Point: 6.4688

>T64669 WP_069054534.1 NZ_CP016464:2014056-2014319 [Bosea sp. RAC05]
MPFEFDPLKSAANLAKHGIDFQQAQALWEDARLLEAPARTEGEPRFMAVGLIGQKHWSAIYVYRGDRVRIISVRRARSEE
IEYYENG

Download         Length: 264 bp

>T64669 NZ_CP016464:2014056-2014319 [Bosea sp. RAC05]
ATGCCATTTGAGTTCGACCCTCTCAAAAGCGCGGCCAACTTGGCCAAGCACGGGATCGATTTCCAACAGGCGCAGGCTCT
TTGGGAGGATGCGCGTCTGCTGGAAGCGCCTGCCCGGACTGAGGGCGAGCCGCGCTTCATGGCAGTGGGACTGATCGGCC
AAAAGCACTGGTCCGCGATTTATGTCTATCGCGGCGATCGGGTGCGTATCATCTCGGTGCGGCGCGCTCGAAGTGAGGAG
ATCGAATACTATGAAAACGGGTGA

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8355.40 Da        Isoelectric Point: 8.7695

>AT64669 WP_069054535.1 NZ_CP016464:2014306-2014527 [Bosea sp. RAC05]
MKTGDFDQAFDDGQSVEDKIDWAKARRPNSETKRVNVDFPSWVVQGLDRQAQHLGVTRQSLIKLWIAERLGKA

Download         Length: 222 bp

>AT64669 NZ_CP016464:2014306-2014527 [Bosea sp. RAC05]
ATGAAAACGGGTGATTTCGATCAGGCTTTCGATGACGGGCAGTCTGTTGAGGACAAAATCGACTGGGCCAAGGCGCGGCG
TCCCAACAGCGAGACGAAGCGCGTGAACGTCGATTTTCCGAGTTGGGTCGTCCAAGGCCTGGACCGTCAGGCGCAGCATC
TCGGCGTGACCCGGCAGTCCCTGATCAAGCTCTGGATTGCGGAGCGACTGGGCAAGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A1B3NJT5

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A1B3NJU0

References