Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1682628..1683217 Replicon chromosome
Accession NZ_CP016464
Organism Bosea sp. RAC05

Toxin (Protein)


Gene name relE Uniprot ID A0A1B3NLD7
Locus tag BSY19_RS11430 Protein ID WP_069054280.1
Coordinates 1682930..1683217 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1B3NK14
Locus tag BSY19_RS11425 Protein ID WP_069054279.1
Coordinates 1682628..1682933 (+) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY19_RS11400 1678004..1678402 - 399 WP_069054274.1 GFA family protein -
BSY19_RS11405 1678446..1679864 - 1419 WP_069054275.1 HAMP domain-containing histidine kinase -
BSY19_RS11410 1679861..1680538 - 678 WP_069054276.1 response regulator transcription factor -
BSY19_RS11415 1680605..1681570 + 966 WP_069054277.1 class I SAM-dependent methyltransferase -
BSY19_RS11420 1681576..1682466 - 891 WP_069054278.1 neutral zinc metallopeptidase -
BSY19_RS11425 1682628..1682933 + 306 WP_069054279.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BSY19_RS11430 1682930..1683217 + 288 WP_069054280.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSY19_RS11435 1683242..1684246 - 1005 WP_069054281.1 cytochrome d ubiquinol oxidase subunit II -
BSY19_RS11440 1684259..1685689 - 1431 WP_069054282.1 cytochrome ubiquinol oxidase subunit I -
BSY19_RS11445 1685798..1686613 - 816 WP_069054283.1 uracil-DNA glycosylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-53)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10607.22 Da        Isoelectric Point: 5.1297

>T64667 WP_069054280.1 NZ_CP016464:1682930-1683217 [Bosea sp. RAC05]
VKLEWGAFALADREALFDWIARESPRAAAIVDERIETAIETLPALPDRGRPGRIAGTREFLIAGTSCIAAYRVSGDTIRV
LRIFHMAQMWPEDLP

Download         Length: 288 bp

>T64667 NZ_CP016464:1682930-1683217 [Bosea sp. RAC05]
GTGAAGCTCGAATGGGGCGCCTTCGCGCTCGCAGACCGCGAGGCGCTCTTTGACTGGATCGCCCGTGAAAGTCCCCGTGC
CGCGGCGATCGTCGATGAGCGCATCGAAACAGCGATCGAGACCTTGCCCGCGCTCCCGGATCGTGGGCGGCCCGGCCGCA
TCGCCGGGACGCGCGAATTCCTGATCGCCGGCACATCCTGCATCGCCGCATACCGCGTCTCGGGCGACACAATCCGCGTG
CTGCGCATTTTCCACATGGCCCAGATGTGGCCCGAGGACCTCCCCTAG

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11056.69 Da        Isoelectric Point: 5.2273

>AT64667 WP_069054279.1 NZ_CP016464:1682628-1682933 [Bosea sp. RAC05]
MASSALVQTRIDPEVKERAAAVLEAVGLTVSDAVRILLTRTANEGALPFELVDPIKQDAWFRAKVLEALADPRPAIPHDE
VKARFAERRRTALEAEAAKEP

Download         Length: 306 bp

>AT64667 NZ_CP016464:1682628-1682933 [Bosea sp. RAC05]
ATGGCATCGAGTGCGCTGGTCCAGACCCGGATCGACCCGGAGGTCAAGGAGCGGGCGGCGGCCGTGCTGGAAGCCGTTGG
ACTGACCGTGTCCGACGCGGTGCGGATCCTCCTCACGCGAACCGCCAATGAGGGCGCGCTTCCGTTCGAACTCGTCGATC
CCATCAAGCAAGACGCATGGTTCCGCGCCAAGGTCCTCGAGGCCCTCGCGGACCCTCGCCCTGCCATCCCGCATGACGAG
GTCAAGGCGCGCTTCGCCGAACGCCGCCGGACGGCCCTGGAGGCAGAGGCCGCGAAAGAGCCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B3NLD7

Antitoxin

Source ID Structure
AlphaFold DB A0A1B3NK14

References