Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 2808732..2809264 Replicon chromosome
Accession NZ_CP016460
Organism Blastomonas sp. RAC04

Toxin (Protein)


Gene name parE Uniprot ID A0A0N0JZM5
Locus tag BSY18_RS14130 Protein ID WP_054135717.1
Coordinates 2808732..2809019 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A0N1BEE5
Locus tag BSY18_RS14135 Protein ID WP_054135718.1
Coordinates 2809016..2809264 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY18_RS14105 2804093..2806072 + 1980 WP_083231654.1 DUF3857 domain-containing protein -
BSY18_RS14110 2806104..2806745 - 642 WP_054135715.1 ankyrin repeat domain-containing protein -
BSY18_RS14115 2806844..2807467 + 624 WP_069050939.1 SCO family protein -
BSY18_RS14120 2807467..2807925 + 459 WP_054135815.1 YcgN family cysteine cluster protein -
BSY18_RS14125 2808009..2808698 + 690 WP_083231655.1 M48 family metallopeptidase -
BSY18_RS14130 2808732..2809019 - 288 WP_054135717.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSY18_RS14135 2809016..2809264 - 249 WP_054135718.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
BSY18_RS14140 2809325..2812999 - 3675 WP_069050940.1 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Antitoxin ParD

(1-81)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10636.02 Da        Isoelectric Point: 5.5999

>T64662 WP_054135717.1 NZ_CP016460:c2809019-2808732 [Blastomonas sp. RAC04]
VKTFVFLPAAEADIEAIWDYSADKWGESQADLYTDEIVHACEALASGSKSSRPVDVRPGLFKCRVSSHVIYFRNTADRIL
VIRVLHGAQDVERNL

Download         Length: 288 bp

>T64662 NZ_CP016460:c2809019-2808732 [Blastomonas sp. RAC04]
GTGAAAACGTTCGTCTTCCTGCCTGCCGCGGAAGCCGATATCGAAGCCATCTGGGACTACAGCGCCGACAAATGGGGTGA
GAGCCAGGCAGACCTCTACACCGATGAAATCGTTCACGCTTGCGAGGCACTTGCCAGCGGCAGCAAGTCAAGCAGGCCAG
TGGATGTGCGACCCGGTCTGTTCAAATGTCGAGTCTCCTCCCACGTCATCTATTTTCGCAATACCGCAGACAGAATCCTC
GTCATCCGGGTGCTGCATGGCGCGCAGGACGTTGAACGAAACCTCTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8936.05 Da        Isoelectric Point: 8.7288

>AT64662 WP_054135718.1 NZ_CP016460:c2809264-2809016 [Blastomonas sp. RAC04]
MARNTSVTIGDHFSGFIAEQVQAGRYGSASDVVRAGLRLLEEHEAKVRALQEALIAGEQSGEPRAIDFEALKARKRAERA
AR

Download         Length: 249 bp

>AT64662 NZ_CP016460:c2809264-2809016 [Blastomonas sp. RAC04]
ATGGCACGCAATACATCGGTTACAATCGGAGACCACTTCTCCGGATTCATCGCTGAACAGGTTCAAGCGGGGCGTTACGG
TTCAGCCAGCGATGTCGTGCGTGCCGGCTTGCGGCTGCTTGAAGAGCACGAGGCGAAGGTCCGCGCATTGCAGGAAGCGT
TGATCGCCGGGGAACAATCCGGCGAACCGCGTGCCATAGATTTTGAAGCATTGAAGGCGCGCAAGCGGGCTGAGCGGGCG
GCCAGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0N0JZM5

Antitoxin

Source ID Structure
AlphaFold DB A0A0N1BEE5

References