Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 581264..581796 Replicon plasmid pBSY16_1
Accession NZ_CP016452
Organism Sinorhizobium sp. RAC02

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BSY16_RS23830 Protein ID WP_069062305.1
Coordinates 581264..581554 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BSY16_RS23835 Protein ID WP_069062306.1
Coordinates 581551..581796 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY16_RS23805 576374..576949 + 576 WP_150130095.1 pyridoxamine 5'-phosphate oxidase family protein -
BSY16_RS23810 577150..578979 + 1830 WP_069061939.1 ABC transporter ATP-binding protein/permease -
BSY16_RS23815 579136..579507 + 372 WP_069061938.1 hypothetical protein -
BSY16_RS23820 579643..580014 - 372 WP_069061937.1 response regulator -
BSY16_RS23825 580192..581242 - 1051 Protein_557 PAS domain-containing protein -
BSY16_RS23830 581264..581554 - 291 WP_069062305.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSY16_RS23835 581551..581796 - 246 WP_069062306.1 CopG family ribbon-helix-helix protein Antitoxin
BSY16_RS23840 582244..583602 + 1359 WP_069062307.1 flagellar biosynthesis protein FlgA -
BSY16_RS23845 583602..583925 + 324 WP_069062308.1 antibiotic biosynthesis monooxygenase -
BSY16_RS23850 583940..584845 + 906 WP_069062309.1 NAD(P)-dependent oxidoreductase -
BSY16_RS23855 584871..585866 + 996 WP_069062310.1 DctP family TRAP transporter solute-binding subunit -
BSY16_RS23860 585944..586495 + 552 WP_069062311.1 TRAP transporter small permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA 1..2220160 2220160


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-34)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11125.97 Da        Isoelectric Point: 10.4120

>T64651 WP_069062305.1 NZ_CP016452:c581554-581264 [Sinorhizobium sp. RAC02]
MTQRRIRWTVRALRRLDEIGAYIEKDDPDAAARVVARLVASVDMLEEQPTVGRIGRLTGTREVVLSDIPYIIPYRVRQDI
DIITVMHASQKWPKRL

Download         Length: 291 bp

>T64651 NZ_CP016452:c581554-581264 [Sinorhizobium sp. RAC02]
ATGACGCAGAGGCGCATCCGCTGGACCGTGCGAGCGTTGCGCCGGCTTGATGAAATTGGTGCGTACATTGAAAAAGACGA
CCCGGATGCCGCTGCACGCGTGGTTGCCCGACTAGTAGCGTCTGTCGACATGTTGGAAGAGCAGCCGACCGTTGGTCGCA
TCGGTCGCCTCACCGGCACGCGCGAAGTTGTATTGTCCGACATTCCCTACATCATCCCTTATCGGGTTCGCCAGGACATC
GATATCATTACGGTGATGCACGCCTCGCAGAAATGGCCGAAAAGGCTGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9096.09 Da        Isoelectric Point: 4.3775

>AT64651 WP_069062306.1 NZ_CP016452:c581796-581551 [Sinorhizobium sp. RAC02]
MTAFTIRVPDEVADRLNQIAQKLDRSRSYMAAQAIEDFVSREEWQLAEVEAGIAEADRGEFASDDEVARVVGKYVKTTSR
S

Download         Length: 246 bp

>AT64651 NZ_CP016452:c581796-581551 [Sinorhizobium sp. RAC02]
ATGACCGCATTCACCATCCGCGTCCCGGACGAAGTGGCCGACCGGCTGAACCAGATTGCTCAAAAGCTCGACCGCTCCCG
CTCTTACATGGCAGCACAAGCCATTGAAGATTTCGTGTCACGCGAAGAATGGCAGCTAGCGGAAGTTGAAGCCGGAATTG
CCGAGGCAGACCGCGGCGAATTCGCCAGTGACGACGAGGTGGCACGCGTGGTCGGTAAATATGTCAAGACGACATCTCGG
TCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References