Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 134546..135078 Replicon plasmid pBSY16_1
Accession NZ_CP016452
Organism Sinorhizobium sp. RAC02

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BSY16_RS21775 Protein ID WP_069061977.1
Coordinates 134788..135078 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BSY16_RS21770 Protein ID WP_069061976.1
Coordinates 134546..134791 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY16_RS21755 132384..133499 - 1116 WP_069061973.1 efflux RND transporter periplasmic adaptor subunit -
BSY16_RS21760 133599..134186 + 588 WP_069061974.1 TetR/AcrR family transcriptional regulator -
BSY16_RS32100 134334..134462 + 129 WP_150130097.1 DUF808 family protein -
BSY16_RS21770 134546..134791 + 246 WP_069061976.1 CopG family ribbon-helix-helix protein Antitoxin
BSY16_RS21775 134788..135078 + 291 WP_069061977.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSY16_RS21780 135310..136218 - 909 WP_083243057.1 LysR family transcriptional regulator -
BSY16_RS21785 136381..137916 + 1536 WP_069061979.1 MFS transporter -
BSY16_RS21790 138121..139083 + 963 WP_069061980.1 DUF808 domain-containing protein -
BSY16_RS21795 139375..139578 + 204 WP_069061981.1 cold-shock protein -
BSY16_RS21800 139602..140041 - 440 Protein_142 DUF1810 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA 1..2220160 2220160


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(4-34)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11038.97 Da        Isoelectric Point: 10.6032

>T64649 WP_069061977.1 NZ_CP016452:134788-135078 [Sinorhizobium sp. RAC02]
MTQRRIRWTVRALRRLDEIGAYIEKDDPDAAARVVARLVASVDMLAELPTVGRIGRITGTREVVLSDIPYIIPYRVRQDI
EIITVMHASQKWPKKL

Download         Length: 291 bp

>T64649 NZ_CP016452:134788-135078 [Sinorhizobium sp. RAC02]
ATGACGCAGAGGCGCATCCGCTGGACCGTGCGAGCATTGCGGCGGCTTGATGAAATCGGTGCGTACATTGAAAAAGACGA
CCCGGATGCCGCTGCACGCGTGGTTGCCCGGCTAGTAGCGTCTGTCGACATGTTGGCAGAGCTGCCGACCGTTGGTCGCA
TCGGTCGCATCACCGGCACGCGCGAAGTCGTATTGTCCGACATTCCCTACATCATCCCTTATCGGGTTCGCCAGGACATC
GAGATCATTACGGTGATGCACGCCTCGCAGAAATGGCCGAAAAAGCTGTAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9110.11 Da        Isoelectric Point: 4.3654

>AT64649 WP_069061976.1 NZ_CP016452:134546-134791 [Sinorhizobium sp. RAC02]
MTAFTIRVPDEVADRLNQIAQKLDRSRSYMAAQAIEDFVSREEWQLAEIEAGIAEADRGEFASDDDVARVVGKYLKTTSR
S

Download         Length: 246 bp

>AT64649 NZ_CP016452:134546-134791 [Sinorhizobium sp. RAC02]
ATGACCGCATTCACCATCCGCGTCCCGGACGAAGTGGCCGACCGGCTGAACCAGATTGCTCAAAAGCTCGACCGTTCCCG
CTCTTACATGGCAGCACAAGCCATTGAAGATTTCGTGTCACGCGAAGAATGGCAGCTAGCGGAAATTGAAGCCGGAATTG
CCGAGGCAGACCGCGGCGAATTCGCCAGTGACGACGACGTGGCACGCGTGGTCGGTAAATATCTCAAGACGACATCTCGG
TCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References