Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1834441..1835072 Replicon chromosome
Accession NZ_CP016450
Organism Sinorhizobium sp. RAC02

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BSY16_RS08825 Protein ID WP_069059313.1
Coordinates 1834441..1834839 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BSY16_RS08830 Protein ID WP_069059314.1
Coordinates 1834839..1835072 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY16_RS08810 1830629..1831708 - 1080 WP_069059310.1 quinolinate synthase NadA -
BSY16_RS08815 1831878..1833113 - 1236 WP_069059311.1 MFS transporter -
BSY16_RS08820 1833413..1834405 + 993 WP_069059312.1 magnesium transporter CorA family protein -
BSY16_RS08825 1834441..1834839 - 399 WP_069059313.1 tRNA(fMet)-specific endonuclease VapC Toxin
BSY16_RS08830 1834839..1835072 - 234 WP_069059314.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
BSY16_RS08835 1835154..1835999 - 846 WP_069059315.1 MOSC domain-containing protein -
BSY16_RS08840 1836079..1836732 - 654 WP_069059316.1 HD domain-containing protein -
BSY16_RS08845 1836769..1839657 - 2889 WP_069059317.1 DUF2339 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

SpoVT-AbrB domain

(7-56)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14783.10 Da        Isoelectric Point: 6.9581

>T64647 WP_069059313.1 NZ_CP016450:c1834839-1834441 [Sinorhizobium sp. RAC02]
MLTYMLDTNICIYVMKTYPPAVREKFNALAEQLCISSITLGELHYGAEKSARRAENLVAIEHFVARLEILPFADKAAAHY
GQVRAELERAGTPCGPHDMQIGGHARSEGLIVVTNNLREFVRMPGVRVENWL

Download         Length: 399 bp

>T64647 NZ_CP016450:c1834839-1834441 [Sinorhizobium sp. RAC02]
ATGCTGACCTATATGCTCGACACCAACATCTGCATCTACGTGATGAAGACCTACCCGCCGGCGGTGCGCGAAAAATTCAA
CGCGCTCGCCGAGCAGCTCTGCATATCGAGCATTACGCTTGGAGAACTGCACTACGGCGCAGAGAAGTCCGCCCGCCGCG
CTGAAAACCTTGTGGCGATCGAGCACTTCGTGGCGCGGCTGGAGATCCTGCCATTTGCCGACAAGGCTGCGGCACATTAC
GGCCAGGTTCGTGCCGAACTGGAACGAGCCGGCACGCCCTGCGGTCCCCACGACATGCAGATCGGTGGCCACGCCCGCAG
CGAGGGGTTGATCGTCGTCACCAACAATCTGCGGGAGTTTGTCCGTATGCCGGGTGTCAGGGTCGAAAACTGGCTGTAA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8756.88 Da        Isoelectric Point: 5.0493

>AT64647 WP_069059314.1 NZ_CP016450:c1835072-1834839 [Sinorhizobium sp. RAC02]
MANSTVFTSNRSQAVRLPKAVAFPEDVHLVDVLKIGRSRVIVPQGQRWDDLFLNGPRVSDDFMSEREQPVAEEREAF

Download         Length: 234 bp

>AT64647 NZ_CP016450:c1835072-1834839 [Sinorhizobium sp. RAC02]
ATGGCCAATTCGACCGTTTTCACCAGCAATCGCAGCCAGGCCGTGCGTCTTCCCAAGGCCGTCGCCTTTCCGGAAGATGT
GCATCTGGTTGACGTCCTCAAGATCGGCCGCAGCCGCGTCATCGTTCCGCAGGGCCAGAGGTGGGACGACCTCTTCCTGA
ATGGGCCGCGCGTCAGCGACGATTTCATGAGCGAACGGGAGCAGCCGGTAGCGGAAGAGCGCGAAGCCTTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References