Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 317359..318026 Replicon chromosome
Accession NZ_CP016450
Organism Sinorhizobium sp. RAC02

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BSY16_RS01475 Protein ID WP_069058030.1
Coordinates 317359..317607 (+) Length 83 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BSY16_RS01480 Protein ID WP_069058031.1
Coordinates 317619..318026 (+) Length 136 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY16_RS01450 312409..312786 + 378 WP_069061301.1 cytochrome c family protein -
BSY16_RS01455 312960..314048 + 1089 WP_069058026.1 hypothetical protein -
BSY16_RS01465 314236..315384 + 1149 WP_069058028.1 hypothetical protein -
BSY16_RS01470 315388..317298 + 1911 WP_069058029.1 AAA family ATPase -
BSY16_RS01475 317359..317607 + 249 WP_069058030.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BSY16_RS01480 317619..318026 + 408 WP_069058031.1 helix-turn-helix domain-containing protein Antitoxin
BSY16_RS01485 318037..319338 + 1302 WP_069058032.1 hypothetical protein -
BSY16_RS01490 319331..320488 + 1158 WP_069058033.1 DUF2333 family protein -
BSY16_RS01495 320715..322394 + 1680 WP_069058034.1 formate--tetrahydrofolate ligase -
BSY16_RS01500 322436..322942 - 507 WP_069058035.1 DUF1993 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-81)

Antitoxin

Cro/C1-type helix-turn-helix domain

(69-123)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9554.06 Da        Isoelectric Point: 10.9839

>T64646 WP_069058030.1 NZ_CP016450:317359-317607 [Sinorhizobium sp. RAC02]
MKQVVFHAPALRTLARIPRNEADRIRRKIYQYATDPETLKANVKKLQGRIGFRLRVGNWRVIFDENGNVLDVLEVDSRGS
IY

Download         Length: 249 bp

>T64646 NZ_CP016450:317359-317607 [Sinorhizobium sp. RAC02]
ATGAAACAGGTTGTCTTCCATGCCCCTGCCTTGCGGACGCTCGCACGGATACCGAGGAACGAGGCCGATAGGATCAGACG
GAAGATTTATCAGTATGCGACTGATCCAGAAACGTTGAAGGCCAACGTAAAGAAGCTCCAGGGACGGATTGGTTTCAGAT
TGCGAGTCGGAAACTGGCGCGTGATCTTTGACGAAAACGGCAACGTACTCGATGTACTCGAAGTCGATAGCCGTGGAAGC
ATTTACTGA

Antitoxin


Download         Length: 136 a.a.        Molecular weight: 15126.06 Da        Isoelectric Point: 4.4131

>AT64646 WP_069058031.1 NZ_CP016450:317619-318026 [Sinorhizobium sp. RAC02]
MNKVTKFTTPSGDEMVVLARAEYDALVEMAEMLEDVAAYDEAKRRIAEGDDLRVPSEFVDRLIDGESPIRVWRDFRGMTS
KDLAKAIGVSAGYLSEIETGKKEGSISVFRSIAKTLRVDLDDLFWGEDSKRSVNE

Download         Length: 408 bp

>AT64646 NZ_CP016450:317619-318026 [Sinorhizobium sp. RAC02]
ATGAACAAGGTAACCAAGTTTACCACGCCAAGCGGTGACGAGATGGTCGTGCTCGCGCGCGCCGAATATGACGCGCTCGT
CGAAATGGCGGAAATGCTTGAAGACGTGGCCGCCTATGACGAAGCCAAGCGGCGCATTGCGGAAGGCGACGACCTCCGGG
TTCCCTCCGAGTTCGTCGACCGACTGATCGACGGGGAAAGTCCGATCCGTGTCTGGCGCGACTTCCGCGGCATGACGAGC
AAGGATCTGGCGAAGGCGATCGGAGTCAGTGCAGGCTATCTTTCCGAGATCGAGACCGGGAAGAAGGAAGGCAGCATTTC
GGTTTTCAGGAGCATTGCCAAGACGCTTCGCGTCGATCTCGACGACCTCTTCTGGGGCGAAGACAGCAAACGGTCGGTAA
ACGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References