Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 955843..956426 Replicon chromosome
Accession NZ_CP016448
Organism Methyloversatilis sp. RAC08

Toxin (Protein)


Gene name vapC Uniprot ID A0A1B3LRY2
Locus tag BSY238_RS04305 Protein ID WP_069038053.1
Coordinates 956043..956426 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1B3LRP1
Locus tag BSY238_RS04300 Protein ID WP_069038052.1
Coordinates 955843..956046 (+) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BSY238_RS04280 951758..952525 + 768 WP_069040446.1 nuclear transport factor 2 family protein -
BSY238_RS04285 952615..953268 - 654 WP_069038050.1 PEP-CTERM sorting domain-containing protein -
BSY238_RS04290 953447..954469 - 1023 WP_083224117.1 alpha/beta hydrolase -
BSY238_RS04295 954942..955652 + 711 WP_083223918.1 PEP-CTERM sorting domain-containing protein -
BSY238_RS04300 955843..956046 + 204 WP_069038052.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BSY238_RS04305 956043..956426 + 384 WP_069038053.1 type II toxin-antitoxin system VapC family toxin Toxin
BSY238_RS04310 956512..956916 - 405 WP_150123879.1 hypothetical protein -
BSY238_RS17950 957094..958173 - 1080 WP_083223919.1 DUF4238 domain-containing protein -
BSY238_RS04315 958341..959594 - 1254 WP_069038055.1 ribonucleotide-diphosphate reductase subunit beta -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-43)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 13985.12 Da        Isoelectric Point: 5.4986

>T64643 WP_069038053.1 NZ_CP016448:956043-956426 [Methyloversatilis sp. RAC08]
VSGILVDASVWVDHFRHGNDSLIQLLDSDLVLIHPLIIGELACGTPPSRAQTLTDLASLQPARQASAAEVLAFINREHLF
GLGFGIVDMHLLASTLITQGARLWTLDKQLDMLAERFGVTRRMERTE

Download         Length: 384 bp

>T64643 NZ_CP016448:956043-956426 [Methyloversatilis sp. RAC08]
GTGAGCGGCATCCTTGTCGATGCCTCGGTGTGGGTGGATCACTTCCGCCACGGTAACGACTCGCTCATCCAGCTTCTGGA
TAGCGACCTCGTACTGATCCACCCGCTGATCATCGGCGAACTGGCCTGCGGCACCCCACCAAGCCGCGCGCAAACACTGA
CCGACCTCGCCAGCCTGCAGCCCGCCCGTCAGGCCAGTGCGGCCGAAGTGCTGGCATTCATCAACCGAGAACACCTGTTC
GGCCTCGGCTTCGGCATCGTAGACATGCACCTGCTCGCCTCTACCTTGATCACGCAAGGCGCCAGATTGTGGACACTGGA
CAAGCAACTGGACATGCTGGCGGAGCGGTTCGGCGTGACTCGTCGAATGGAGCGCACTGAGTGA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7460.49 Da        Isoelectric Point: 4.9803

>AT64643 WP_069038052.1 NZ_CP016448:955843-956046 [Methyloversatilis sp. RAC08]
MRTTVTIDDALYERALEVADPSMDKADLFREAIKTYVRVQSARRLAALGATQPDMPDIPRARADAPQ

Download         Length: 204 bp

>AT64643 NZ_CP016448:955843-956046 [Methyloversatilis sp. RAC08]
ATGAGAACGACCGTGACGATAGATGACGCCCTGTACGAGCGGGCGCTTGAAGTGGCCGATCCGTCCATGGACAAGGCCGA
CCTGTTCCGCGAAGCAATCAAGACCTATGTCAGGGTGCAGTCGGCCAGACGGCTCGCCGCGCTGGGCGCAACCCAGCCCG
ACATGCCGGACATTCCGCGCGCGCGGGCTGACGCCCCCCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1B3LRY2

Antitoxin

Source ID Structure
AlphaFold DB A0A1B3LRP1

References